阿替洛尔治疗充血性心力衰竭的临床观察  

A clincal Observation of Atenolol Therapy for Congestive Heart Failure

作　　者：张新超[1] 魏宁[1] 洛银宝 

机构地区：[1]宁夏医学院附属医院心血管内科,内蒙鄂托克前旗医院

出　　处：《宁夏医学杂志》1994年第6期337-339,共3页Ningxia Medical Journal

摘　　要：给３８例扩张型心肌病充血性心力衰竭（ＣＨＦ）在充分强心、利尿、扩血管治疗两周以上的基础上加用了小剂量阿替洛尔（Ａｔｅｎｏｌｏｌ）４～６周。结果显示，３４例患者的临床心功能得到改善，总有效率８９．５％，其中伴有心动过速（Ⅰ组）２８例的心功能改善显效率为６４．３％，不伴有心动过速（Ⅱ组）１０例的心功能改善显效率仅２０．０％（２／１０）；左室射血分数增加，Ⅰ组从０．２６±０．０５增至０．４０±０．０６，Ⅱ组从０．３２±０．０４增至０．３８±０．０５。小剂量Ａｔｅｎｏｌｏｌ治疗ＣＨＦ安全有效，对伴有心动过速的严重ＣＨＦ尤其能产生良好的作用。To evaluate the eff-ect of beta-adrenergic blockade in severe congestive heart failure C-H,was given to 38 in such CHF patients (mean age 40.6 yrs)with dillated (ardiomyopathy,divided into group I with tachycardia 28 cases) and group II without tachyc-ardia(10 cases)low-dose atenolol After 4─6 weeks treatment, the cli-nical heart ftnction(NYHA)in 34 cases was improved and the total effective rate was 89.5 per cent. There were increases in ejection fraction from 0.26±0.05 to 0.40±0.06 (P<0.001)in group I and from 0.32±0.04 to 0.38±0.05(P<0.05) in group I. Also,there was a decreasc in the left ventricular end-diastolic dimension from 0.69cm to 0.60cm (P>0.00It is concluded that ateno-lol reatlly has beneficial clinical and hemodynamic effects in patients With CHF.

关 键 词：心力衰竭 充血性 治疗 阿替洛尔 

分 类 号：R541.610.5[医药卫生—心血管疾病] R972.1[医药卫生—内科学]