乙型慢性活动性肝炎血清微量元素与肝功和HBeAg关系的研究  

STUDY ON THE RELATIONSHIP BETWEEN TRACE ELEMENTS AND LIVER FUNCTION, HBeAg IN PATIENTS WITH CHRONIC ACTIVE HEPATITIS B

作　　者：王磊[1] 华玉瑛 李心河[1] 王金声[1] 刘韶平 潘沛恩[1] 

机构地区：[1]济南市传染病医院

出　　处：《山东医科大学学报》1994年第2期134-137,共4页Acta Academiae Medicinae Shandong

摘　　要：采用ＤＣＰ－ＡＥＳ法同步检测了３２例乙型慢性活动性肝炎（ＣＡＨ－Ｂ）的血清锌、铁、铜、锰、镍、钴、锂、铬、钙、镁；以及血清ＡＬＴ、胆红素、ＧＧＴ、白蛋白、球蛋白和ＨＢｅＡｇ。结果表明，ＣＡＨ－Ｂ血清微量元素存在着失衡。锌、铁、铜／锌比值、锰有明显改变，其改变与血清胆红素、白蛋白、球蛋白等指标异常有密切关系；铜、锂、钴有轻度改变；铜、钴、铜／锌比值的异常改变可能与ＨＢｅＡｇ有某些联系。Ten kinds of the serum trace elements, including Zn, Fe, Cu, Mn, Ni, Co, Li, Cr, Ca, Mg were determined by DCP-AES method in 32 patients with chronic active hepatitis B (CAH-B); and HBeAg, many indexes of liver function ( ALT, bilirubin, γ-IGT, albumin, globulin ) were simultaneously tested.The results showed that there were obvious changes of the serum Zn, Fe, Mn and Cu/Zn ratio in these patients, which were closely related to the abnormalities of bilirubin, albumin and globulin; there were minor abnormalities of the Cu, Co and Li; these changes of the Cu, Co and Cu/Zn ratio were probably related to HBeAg.

关 键 词：乙型肝炎 E抗原 微量元素 

分 类 号：R512.62[医药卫生—内科学]