血管紧张素对大鼠饮盐水行为的作用  

EFFECT OF ANGIOTENSIN ON SALT INTAKE BEHAVIOR OF RAT

作　　者：杨振芳[1] 幺淑珍[1] 

机构地区：[1]天津医学院解剖教研室,天津医学院卫化教研室

出　　处：《生理学报》1994年第2期187-192,共6页Acta Physiologica Sinica

摘　　要：在ＳＤ大鼠静脉内注入不同剂量的ＡｕｇⅡ后大鼠的饮盐水量明显增加。切除肾上腺的大鼠也出现强烈的饮盐水行为，但给予适当量的难固酮可消除这种行为。脑室内注入巯甲丙脯酸可阻断静脉内给与ＡｎｇⅡ所引起的大鼠的饮盐水行为。本文对ＡｎｇⅡ的作用机理进行了探讨。Intravenous infusion of varinus doses of Aug Ⅱ caused significant increases ofthe salt intake in S-D rats as a result of natriuretic action of the drug.The phenomenon could be abolished by administration of aldosterone but unaffected by adrenalectomy.Captoptil could suppress the Ang Ⅱ effect.Discrepancies with a previous work on the interpretation of the action mode of Aug Ⅱwere discusseed.

关 键 词：血管紧张不Ⅱ 静脉灌流 饮盐 

分 类 号：R965[医药卫生—药理学]