36例慢牲肾功能不全患者血浆心钠素水平的观察  

INVESTIGATI0N 0F PLAsMICATRIAL NATRIURETIC PEPTIDE LEVEL IN 36CASES 0FCHR0NIC RENAL INSUFFICIENCY

作　　者：赵庆平[1] 张焕轶[1] 滕清良[1] 

机构地区：[1]泰山医学院第一教学医院,泰安卫生学校内科教研室

出　　处：《泰山医学院学报》1994年第2期120-123,共4页Journal of Taishan Medical College

摘　　要：报告３６例慢性肾功能不全患者的血浆心钠素、肾素、血管紧张素Ⅱ、醛固酮水平及其相互关系。结果表明：①慢性肾功能不全患者的血浆心钠素水平明显高于对照组值（Ｐ＜０．０ｌ）；②慢性肾功能不全患者中并发高血压者与血压正常者血浆心钠素水平相近，但均高于对照组（Ｐ＜０．０１）；③慢性肾功能不全患者肾素—血管紧张素—醛固酮系统（ＲＡＡＳ）活性增高，但心钠素与醛固酮无明显相关。提示血浆心钠素测定在慢性肾功能不全的诊断中有重要意义。The levels of plasmic atrial natriuretic peptide(ANP ),renin,angi-oltensin Ⅱand aldosterone in 36 csses of chronic renal insufficiency were reported.The results showed that:①the plasmic ANP level was apparantly higher in patients With chronic renal insufficiency than that in the control group(P<0. 0l )②the plasmic An- Plevel chronic renal insufficiency patients With and Without high blood pressure showed no difference,but both were higher than that of the control group (P<0.0l ).③the ac-tivity of the Renim-Angiotensin-Aldosterone system (RAAS) increased in patientswith Chronic renal instuffciency,but the level of ANP had no correlation with the level of aldosterone. All these suggest that examinations of plasmic ANP had significant impor-tance in the diagnosis of chronic renal insufficency.

关 键 词：肾功能不全 心钠素 高血压 

分 类 号：R692.5[医药卫生—泌尿科学]