肾性骨病80例临床分析  

Clinicai Analysis in Patients with Chronic Renal Osteodystrophy

作　　者：朱淑兰[1] 王维力[1] 林珊[1] 赵立全[1] 翟德佩[1] 

机构地区：[1]天津医科大学总医院,300052

出　　处：《天津医药》1994年第12期726-729,共4页Tianjin Medical Journal

摘　　要：报告80例肾性骨病和钙、磷代谢变化的关系。其中男41例,女39例。发病年龄8～71岁,平均44岁。平均病程3.14±1.43年(1～10年)。骨质变化以骨质疏松居多占38例,骨软化和/或肾性佝偻病12例,纤维囊性骨炎10例,骨硬化10例。10例发生骨折。血钙平均值低于正常,血磷升高。24小时尿磷及尿钙减少。血清甲状旁腺激素(PTH)、降钙素(CT)、骨钙素(BGP),酸性磷酸酶(ACP)、抗酒石酸酸性磷酸酶(TrACP)及碱性磷酸酶(AKP)升高,均有显著性差异。Eighty cases of chronic renal osteodystrophy (41 men and 39 women) associated with metabolic changes of calcium and phosphorus were reported. Their mean age was 44 years (8-71).The average course was 31.4 years(1-10). Roentgenological examinations revealed o-steoporosis in 38 cases. osteomalacia or renal rickets in 12 cases, osteitis fibrosa in 10 cases and osteosclerosis in 10 cases. Ten patients had fractures. The mean value ef serum Ca decreased, and an increased serum P was found in 80 patients. Urinary P and Ca concentrations of 24 hours were decreased. The mean value of serum PTH, calcitonin.bone Gla-protein, acid phosphatase, tartrate-resistant acid phosphatase and AKP were increased.

关 键 词：肾性骨病 骨钙素 酸性磷酸酶 钙 磷 临床分析 

分 类 号：R681[医药卫生—骨科学]