眼结膜印迹细胞法(CIC)与血清VitA浓度测定法的比较研究  

Comparative study of conjunctival impression cytology (CIC) with serum vitamin A concentration assay method.

作　　者：罗海英[1] 邢杰[1] 金萍[2] 徐萍[1] 

机构地区：[1]吉林大学第二医院儿童保健科,130041 [2]长春市朝阳区疾病预防控制中心儿保科

出　　处：《中国妇幼保健》2005年第5期580-581,共2页Maternal and Child Health Care of China

摘　　要：目的:确定眼结膜印迹细胞法(CIC法)用于儿童群体亚临床Vit A缺乏(SVAD)早期筛查的可行性.方法:采用CIC法,对438例3～7岁学龄前儿童进行Vit A营养状况评价,评价结果与血清Vit A水平相比较.结果:①随着血清VitA水平的降低结膜印迹细胞异常程度也相应增加(P＜0.05),两者的符合率为93.17%.②有26.38%(110/410)的研究对象结膜印迹细胞出现异常改变,提示CIC法可以早期发现SVAD.结论:CIC法是一种能够有效地评价儿童机体Vit A营养状况,早期发现SVAD的快捷方法.Objective:To determine the feasibility of conjunctival impression cytology (CIC) used in the early screening of children with subclinical vitamin A deficiency (SVAD).Methods:With CIC method, the nutrition status of 438 children aged 3~7 years old were evaluated and compared with serum vitamin A concentration.Results:① With the levels of serum vitamin A decreased, the abnormal degree of CIC increased accordingly (P<0.05).The coincidence rate of two methods was 93.17%.② The abnormal rate of CIC was 26.83%, which suggested CIC method could detect early subclinical vitamin A deficiency.Conclusion:CIC is a quick and objective method for effective assessment of vitamin A status of children and early detection on SVAD.

关 键 词：眼结膜印迹细胞血清Vit A 亚临床Vit A缺乏 

分 类 号：R179[医药卫生—妇幼卫生保健]