异位并列心脏及单侧肺同种移植实验研究初步报告  

Preliminary Report of Experimental Study in Heterotopic Heart-Single Lung Transplantation

作　　者：张良华[1] 沈远仲 潘友民[1] 胡宗英[1] 

机构地区：[1]同济医科大学附属同济医院胸心外科,武汉430030

出　　处：《同济医科大学学报》1994年第3期235-237,共3页Acta Universitatis Medicinae Tongji

摘　　要：1991～1993年在常温、不用体外循环并以气管插管静脉复合麻醉下，进行18例犬的胸内异位并列心脏及单侧肺移植的实验研究，其中有17例术毕供心复跳并恢复了自主呼吸，心肺复苏率达94.4％。实验犬术后有1例存活2d，余16例存活在1d内。本实验初步探讨了非灵长类动物心肺移植的方法以及本术式对保存自主呼吸的优越性。From 1991 to 1993,18 experimental heterotopic heartsingle lung transplan tation(HHSLT)were performed on canines under normothermia without cardiopulmonary bypass.12 of them were of heterotopic heart-right lung transplantation type(HHRLT)and the other 6 were of heterotopic heart-Left lung transplantation type(HHLLT).The total recovery rate of donor heart beat and respiration was 94.4％.The longest survival time after HHSLT was 2 days,One dog died during operation,and the rest 16 canines survived for one day.Subprimate animals like dog and swine are not good subjects for combined heart and bilateral lung transplants,because bilateral pulmonary denervation can not provide autonomous respiration for the subprimate after HHSLT,so death occurred during operation.Our method of HHSLT could provide a functional heart-lung allograft.

关 键 词：心脏移植 肺移植 自主呼吸 

分 类 号：R654.2[医药卫生—外科学]