饮红茶对大鼠慢性缺氧性肺动脉高压的影响  

Effect of Black Tea on Chronic Hypoxic Pulmonary Hypertension in Rats

作　　者：陈丽玲[1] 郭小林 王珏 苏伟 周群 范明[1] 王迪浔[1] 

机构地区：[1]同济医科大学基础医学院病理生理学教研室,武汉430030

出　　处：《同济医科大学学报》1994年第5期356-358,共3页Acta Universitatis Medicinae Tongji

基　　金：国家"八五"重点课题资助

摘　　要：慢性缺氧过程中，饮红茶的大鼠（HT组）平均肺动脉压（Ppa）为2.50±0.20kPa，肺血管阻力（PVR）为2824.80±658.69kPa·s^(-1)／L，均显著低于缺氧对照组（Ppa为2.97±0.25kPa，PVR为3763.46±529.62kPa·s^(-1)／L），而HT组肺血管对急性缺氧的反应性（22.50±6.16％）则显著强于缺氧对照组（10.65±3.80％）。结果表明，长期饮红茶可防止大鼠慢性缺氧性肺动脉高压的形成。In this study,effect of black tea on chronic hypoxic pulmonary hypertension was examined.Mean pulmonary artery pressure (Ppa ) (2.97±0.25 kPa) and pulmonary vascular resistance (PVR) (3 763.46±529.62 kPa·s^(-1)/L) were higher in chronic hypoxic rats than those in nortnoxic rats (2.66±0.12 kPa and 2 857.21±496.40 kPa·s(-1)/L).Right ventricular hypertrophy was remarkable after hypoxia.In hypoxic but tea-given rats,hypoxic pulmonary hypertension and right ventricular hypertrophy were attenuated,and no change was found in hypoxic pulmonary vascular reactivity.The result suggested black tea could prevent chronic hypoxic pulmonary hypertension and ventricular hypertrophy.

关 键 词：茶 缺氧症 高血压 肺血管反应性 肺动脉高压 

分 类 号：R543.2[医药卫生—心血管疾病] R282.71[医药卫生—内科学]