呋喃甲酰基吡唑啉酮缩氨基硫脲配合物的合成、光谱表征及生物活性  

Synthesis, Spectral Characterization and Bioactivity of Complexes ofFuroylpyrazolone-Thiosemicarbazone

作　　者：李锦州[1] 张光林[1] 沙靖全[1] 安郁美[1] 

机构地区：[1]哈尔滨师范大学化学系,黑龙江哈尔滨150080

出　　处：《光谱学与光谱分析》2005年第2期216-218,共3页Spectroscopy and Spectral Analysis

基　　金：黑龙江省自然科学基金(B0106);教育部重点科学研究计划;黑龙江省教育厅科技(10541082)资助项目

摘　　要：合成了含硫席夫碱试剂1苯基3甲基4(α呋喃甲酰基)吡唑啉酮5缩氨基硫脲(HL)及其Zn(Ⅱ),Cd(Ⅱ),Co(Ⅱ)配合物。元素分析及摩尔电导值表明新配合物的组成为[ZnL2]·15H2O,[CdL2]·C2H5OH和[CoL2]·H2O。运用红外光谱、紫外光谱、核磁共振谱和磁矩,对配合物进行了表征。抗菌实验表明配合物具有较强的抗菌生物活性。A new Schiff base containing sulphur, 1-phenyl-3-methyl-4-(alpha-furoyl)pyrazolone-5-thiosemicarbazone (HL) and its Zn (II), Cd(II) and Co(II) complexes have been synthesized. On the basis of elemental analysis and molar conductance, the general formulae of the complexes, [ZnL2]-1.5H(2)O, [Cdl(2)]-C2H5OH and [Col(2)]-H2O, were given. They were characterized by IR, UV-Visible, H-1 NMR, C-13 NMR and magnetic moments. The results show that the metal ions exhibit coordination of six in the complexes. The antibacterial experiments indicate that they have high antibacterial activities against S. aureus, B. subtilis, E. coli, E. carotovora, and C. flaccumfaciens.

关 键 词：氨基硫脲 Co(Ⅱ)配合物 吡唑啉酮 酰基 光谱表征 席夫碱 磁矩 合成 呋喃 甲基 

分 类 号：O626[理学—有机化学] O641.4[理学—化学]