鹿茸角发育与再生机理  

The Mechanisms of Deer Antlers Development and Regeneration

作　　者：岳占碰[1] 邓旭明[1] 冯海华[1] 

机构地区：[1]吉林大学兽医学院,长春130062

出　　处：《经济动物学报》2005年第1期46-49,共4页Journal of Economic Animal

基　　金：国家自然科学基金项目 (3 0 3 71 0 3 2 );教育部留学回国人员科研启动基金项目 (2 0 0 3年第 2 3批 )

摘　　要：对鹿茸角发育与再生调节机理的研究进展进行了综述,并对与鹿茸角发育与再生相关的一些生理问题进行了探讨。已确认的与鹿茸角再生关系密切的重要分子有甲状旁腺激素相关肽、视黄酸、胰岛素样生长因子等,这些物质广泛分布于芽基及快速生长的鹿茸角内,可调节软骨细胞、成骨细胞及破骨细胞的分化。由于鹿茸角再生过程与生殖周期密切相关。There is a unique model of mammalian organ regeneration and wound repair. But the underlying mechanisms of regeneration remain poorly understood. This article reviews what is currently known about the local and systemic regulation of antler development and regeneration and some of the related unsolved questions of antler physiology is discussed. Molecules that have been identified as having potentially important local roles in antlers include parathyroid hormone-related peptide, retinoic acid (RA) and insulin-like growth factors (IGFs). All of them are present in the blastema and in the rapidly growing antler where they regulate the differentiation of chondrocytes, osteoblasts and osteoclasts. The trigger that regulates the expression of these local signals is likely to be changing levels of sex steroids because the process of antler regeneration is linked to the reproductive cycle.

关 键 词：鹿茸角 发育 再生 作用机理 甲状旁腺激素 视黄酸 胰岛素样生长因子 

分 类 号：S865.42[农业科学—野生动物驯养]