固相萃取GC-MS法测定通栓醒脑注射液中冰片和麝香酮的含量  

Determination of Borneol and Muscone in Tongshuanxingnao Injections with Solid-phase Extraction and GC-MS

作　　者：张守尧[1] 王鹏[1] 张忠义[1] 吴惠勤[2] 

机构地区：[1]第一军医大学珠江医院,广东广州510282 [2]中国广州分析测试中心广东省化学危害应急检测技术重点实验室,广东广州510070

出　　处：《分析测试学报》2005年第2期104-105,108,共3页Journal of Instrumental Analysis

摘　　要：建立通栓醒脑注射液中冰片和麝香酮含量的测定方法.采用固相萃取法处理样品,用GC-MS法同时分离测定冰片和麝香酮的含量.冰片和麝香酮的回收率和相对标准偏差分别为97.8%～104.8%,2.72%和97.6%～105.4%,3.86%.本法快速准确,可用于通栓醒脑注射液的质量控制.An assay methods for measuring borneol and muscone in Tongshuanxingnao injections was estabˉlished.Borneol and muscone were extracted with a solid-phase extraction procedure and were simultaneously measured with GC-MS method after a solid-phase extraction procedure.The recoveries and relative standard deviation were97.8%～104.8%and2.72%for borneol and97.6%～105.4%and3.86%for muscone,respectively.The method was simple and accurate and can be used for the quality control of Tongshuanxingˉnao injections.

关 键 词：固相萃取 GC-MS 通栓醒脑注射液 冰片 麝香酮 

分 类 号：O657.63[理学—分析化学] R972[理学—化学]