Q波型AMI患者CK/CK-MB峰值与心功能损伤程度的相关分析  

THE ANALYSIS OF CORRELATION BETWEEN PEAK VALUE OF CK/CK-MB AND INJURED DEGREE OF CARDIAC FUNCTION FOR Q-WAVE TYPE OF ACUTE MYOCARDIAL INFARCTION

作　　者：符青松[1] 张鑫地[1] 谢家祥[1] 吴清艳[1] 

机构地区：[1]海南医学院检验医学系2001级本科班,海口570102

出　　处：《海南医学院学报》2005年第1期27-29,共3页Journal of Hainan Medical University

基　　金：海南省自然科学基金资助课题(NO:30214)

摘　　要：目的:分析肌酸激酶及其同工酶(CK/CK-MB)峰值与Q波型急性心肌梗死(AMI)患者心功能损伤程度之间的相关关系。方法:根据心电图上是否出现梗死性Q波(病理性Q波)把65例AMI患者分为两组:Q波组56例,非Q波组9例;用CK/CK-MB作为AMI的标志,用超声心动图测定的射血分数(EF%)衡量心功能。结果:Q波组与非Q波组之间的平均年龄、平均CK峰值、平均CK-MB峰值均无显著性差异;在治疗前,Q波组与非Q波组之间的平均CK值、平均CK-MB值均无显著性差异;Q波组中平均CK/CK-MB峰值与平均EF%值呈负相关关系;非Q波组中平均CK/CK-MB峰值与平均EF%值不呈相关关系。结论:Q波型AMI患者心肌细胞损伤越严重,其心功能越难恢复。Objective:To analyze the correlation between the peak value of the creatine kinase )CK( to its cardiac-muscle-specific MB isoengyme (CK-MB) and the injured degree of the cardiac function for Q-wave type of acute myocardial infarction (AMI)(. Methods:Sixty-five patients with AMI were divided into two groups according the electrocardiogram with or without infarctional Q-wave:the Q-wave group (56 cases) and the non-Q-wave group (9 cases). The CK and CK-MB was used as the indicator of AMI , and the cardiac function was evaluated by Ejection Fraction (EF %)?Results:The average age?the average CK and CK-MB peak value of two groups were not significantlydifferent;the average CK and CK-MB value before treatment of two groups were not significant ifference either. There was a negative correlation between the average CK and CK-MB peak value and the average EF % value in Q wave group: there was not the correlation between the average CKand CK-MB peak value and the average EF % value in no-Q wave group. Conclusion:The more seriousthe myocardial cell is injured,the more difficult to recover for the patients with Q wave type of AMI.

关 键 词：Q波 CK-MB AMI 患者 心功能 心电图 相关关系 EF 结论 显著性差异 

分 类 号：R542[医药卫生—心血管疾病] R541[医药卫生—内科学]