^(18)氟脱氧葡萄糖显像正电子发射体层摄影术在肝移植受者筛选中的应用  

Application of ^(18) F-FDG imaging in screening of the recipients with liver transplantation

作　　者：许泽清[1] 李怀富[2] 宋家武[3] 郑克立[2] 

机构地区：[1]中山大学附属第五医院核医学科,广东省珠海市519000 [2]中山大学附属第五医院移植科,广东省珠海市519000 [3]中山大学附属第五医院消化科,广东省珠海市519000

出　　处：《中华器官移植杂志》2005年第3期142-144,共3页Chinese Journal of Organ Transplantation

摘　　要：目的　探讨18氟脱氧葡萄糖(18F FDG)符合线路显像在肝移植受者筛选中的临床应用价值。方法　应用正电子发射体层摄影术,对16例原发性肝癌患者及21 例肝硬化失代偿期患者进行18F FDG符合线路显像,并与CT图象进行图象融合,根据18 F FDG显像及融合图象18 F FDG的浓集情况判断有无肝外恶性肿瘤灶存在。此前的常规检查中,37 例均未发现肝外恶性肿瘤(包括肝外原发肿瘤及肝癌肝外转移灶)。结果　21例肝硬化失代偿期患者中有5 例发现肝外原发肿瘤灶及转移灶,16例原发性肝癌患者中有7例发现肝癌肝外转移病灶。结论　利用18 F FDG的正电子发射体层摄影术能发现其它检查所不能发现的肝外肿瘤,能为肝移植受者的筛选提供较多有价值的信息。Objective To discuss the clinical values of 18 F-FDG imaging in screening of the recipients with liver transplantation.Methods By using positron emission tomography, 16 case of hepatocellular carcinoma and 21 case of hepatic cirrhosis with discompensation were subjected to 18 F-FDG imaging. The obtained images were fused with CT images. According to the result of the abnormal 18 F-FDG uptake in 18 F-FDG imaging and image fusion with CT imaging, extrahepatic malignant tumor was judged. The initial routine examinations showed no extrahepatic malignant tumor in these 37 cases , including primary extrahepatic carcinoma and extrahepatic metastasis of liver carcinoma.Results Among the 21 case of hepatic cirrhosis with discompensation, there were 5 cases of extrahepatic primary carcinoma and metastasis. In 16 cases of primary hepatocellular carcinoma, there were 7 cases of extrahepatic metastasis.Conclusion 18 F-FDG positron emission tomography imaging can find the extrahepatic carcinomas which can not be discovered by other examinations, which can provide more information for screening of the recipients undergoing liver transplantation.

关 键 词：正电子发射体层摄影术 肝移植 ^18F-FDG ^18氟脱氧葡萄糖 肝外 患者 受者 发现 结论 图象 

分 类 号：R657.3[医药卫生—外科学]