清络通痹颗粒的质量标准研究  

Study on the Quality Standard for Qingluotongbi Granules

作　　者：董洁[1] 陈峰[1] 沈静[1] 郭立玮[1] 

机构地区：[1]南京中医药大学植物药深加工工程中心,江苏南京210029

出　　处：《时珍国医国药》2005年第2期99-100,共2页Lishizhen Medicine and Materia Medica Research

基　　金：江苏省高校高新技术产业化资助项目(No.SH01041)

摘　　要：目的:建立清络通痹颗粒(生地黄、三七、桑寄生、青风藤等)的质量控制方法。方法:采用薄层色谱法对清络通痹颗粒中的生地黄、三七、桑寄生进行定性鉴别;并采用HPLC法对该药中的青藤碱进行含量测定。结果:鉴别项下的阴性对照无干扰,专属性强;青藤碱在0.125-1.25μg范围内呈良好的线性关系,相关系数r=0.999 9,平均回收率为100.9％,RSD=1.76％。结论:该法操作简便、结果准确,重现性好,可以控制清络通痹颗粒的质量。Objective: To establish the quality control standard for Qingluotongbi Granules. Methods: Radix Rehmanniae, Radix Notoginseng.Herba Taxilli were indentified by TLC. The content of sinomenine were determined by HPLC. Results: The spots on TLC plates were clear without interference in the blank reference. The liner range of sinomenine was 0. 125-1. 25 μg,r=0. 999 9. The average recovery of sinomenine was 100. 9% and RSD was 1. 76%. Conclusion:The method is simple,accruate,reproducible and can be used as the quality control method for Qingluotongbi Granules.

关 键 词：清络通痹颗粒 生地黄 三七 桑寄生 青藤碱 薄层色谱 高效液相色谱 

分 类 号：R284.1[医药卫生—中药学] R284.2[医药卫生—中医学]