显臣粉刺净酊抗过敏止痒作用的研究  

Experimental Study on the Antiallergic and Antipruritic Effect of Tinctura Xianchen Fenci Jing

作　　者：廖松岩[1] 董淑英[1] 吴华璞[1] 

机构地区：[1]蚌埠医学院药学系药理教研室,安徽蚌埠233003

出　　处：《时珍国医国药》2005年第2期121-121,共1页Lishizhen Medicine and Materia Medica Research

摘　　要：目的:研究显臣粉刺净酊抗过敏止痒作用。方法:以4-氨基吡啶(4-AP)诱发小鼠舔体反应为指标,观察显臣粉 刺净酊的抗过敏止痒作用。结果:显臣粉刺净酊1.0 ml使小鼠舔体次数明显减少,与对照组比较,差异有显著性(P< 0.01)。结论:显臣粉刺净酊对4-AP引起的过敏致痒反应有明显的抑制作用,呈一定的量效关系。Objective: To study the antiallergic and antipruritic effect of Tinctura Xianchen Fenci Jing on mice. Methods:4 -aminopyridine (4-AP) (1 mg·kg-1) was used to induce a licking response in mice. The antiallergic and antipruritic effects were observed. Results: The licking response in mice of Tinctura Xianchen Fenci Jing group at scruff decreased significantly compared with that in control group (P<0. 01). Conclusion: Tinctura Xianchen Fenci Jing has antiallergic and antipruritic effects.

关 键 词：显臣粉刺净酊 4-氨基吡啶 抗过敏止痒 

分 类 号：R285.5[医药卫生—中药学]