实时荧光定量PCR测定早孕子宫蜕膜白血病抑制因子的研究  

Quantitative Determine of Real-time Fluorescent PCR on the Expression of Leukemia Inhibitory Factor(LIF) in Early Pregnant Decidua

作　　者：武泽[1] 任平[1] 周蓉 邓波[1] 章晓梅[1] 邵静宜[1] 方敏[1] 

机构地区：[1]云南省第一人民医院生殖遗传科,昆明650032 [2]上海久盛医疗用品有限公司

出　　处：《中国计划生育学杂志》2005年第2期104-106,共3页Chinese Journal of Family Planning

基　　金：云南省自然科学基金资助项目(2 0 0 1C0 0 36Q)

摘　　要：目的 :探讨白血病抑制因子 (LIF)在人类早孕蜕膜组织的表达情况。方法 :采用实时荧光定量PCR技术 ,对 36例正常早孕妇女子宫蜕膜进行定量检测。结果 :36例蜕膜组织均有LIF表达 ,表达水平中位数为 4 6 .5 0 pg/ml。结论Objective: To investigate the expression of LIF in 36 cases of early pregnant women's decidua. Methods: LIF gene expression was detected in early pregnant deciduas by real-time fluorescent quantitative PCR. Results: LIF expressed in all cases. The expression median was 46.50pg/ml. Conclusion: The expression of LIF in deciduas is related with early pregnancy maintaining.

关 键 词：子宫蜕膜 早孕期 白血病抑制因子 蜕膜组织 实时荧光定量PCR 表达水平 正常 LIF 人类 基因表达 

分 类 号：R446.9[医药卫生—诊断学]