绞股蓝总皂甙对体外培养肺癌细胞的抑制作用  

THE SUPPRESSION EFFECT OF GYPENOSIDES ON CULTURED LUNG CARCINOMA CELL LINES

作　　者：刘华[1] 司履生[1] 

机构地区：[1]西安医科大学免疫病理学研究室,西安710061

出　　处：《西安医科大学学报》1994年第4期346-348,共3页Journal of Xi'an Medical University(Chinese)

摘　　要：利用绞股蓝总皂甙(GP)对5株不同的体外培养实体癌细胞株增殖的影响,发现GP的抑瘤作用随细胞株来源不同有明显的差异。当GP浓度为1～10mg/L时,对肺癌细胞株A549、Calu 1、592/9的抑制作用明显强于宫颈癌Hela S_3及结肠腺癌Colo 205,而同样浓度的GP却能促进正常人的混合淋巴细胞反应。The suppression effect of Gypeno-sides (GP) on cultured carcinoma cells was observed in the present experiment. We found the suppres-sion effect varied with different cell lines. With 10 mg/L GP. the proliferation of lung carcinoma cellsA549, Calu 1, 592/9 were suppressed much morestrongly than cervical carcinoma Hela S3 and colonadnocarcinoma Colo 205. Meanwhile, instead sup-pression effect, GP could enhance mixed lymphocytereaction at the same concentration.

关 键 词：绞股蓝 癌细胞株 细胞增殖反应 淋巴细胞 总皂甙 

分 类 号：R282.710.5[医药卫生—中药学] R285.6[医药卫生—中医学]