正交投影分光光度法同时测定联磺甲氧苄啶片中的SMZ和TMP  

SIMULTANEOUS DETERMINATION OF SMZ AND TMP IN SULFAMETHOXAZOLE SULFADIAZINE AND TRIMETHOPRIM TABLETS BY THE ORTHOGONAL PROJECTION SPECTROMETRY

作　　者：方洪壮[1] 吴刚[1] 孙长海[1] 

机构地区：[1]佳木斯大学药学系,佳木斯154007

出　　处：《化学分析计量》2005年第2期22-24,共3页Chemical Analysis And Meterage

摘　　要：采用正交投影分光光度法同时测定 3组分复方药物联磺甲氧苄啶片中磺胺甲恶唑 (SMZ)和甲氧苄啶(TMP)二组分的含量。SMZ和TMP的平均回收率分别为 99. 6%和 99. 4%,测定结果的相对标准差分别为 0. 75%和0. 60%。讨论了波长区间和波长间隔对测定结果的影响。Two ingredients in sulfamethoxazole sulfadiazine and trimethoprim tablets were determined simultaneously by orthogonal projection spectrophotometry. The recoveries of sulfamethoxazole and trimethoprim were 99.6% and 99.4%, the relative standard deviation were 0.75% and 0.60% respectively. The effects of wavelength on the analytical results were discussed.

关 键 词：甲氧苄啶 SMZ TMP 测定结果 复方药物 磺胺甲恶唑 同时测定 平均回收率 含量 标准差 

分 类 号：O657[理学—分析化学] R927.2[理学—化学]