新生儿窒息血清心肌酶谱检测及临床意义  

Clinical Significance of Detection of Myocardial Zymogram in Serum During the Asphyxia of Neonate

作　　者：舒蕾[1] 杨娅华[1] 杨沧[1] 苗丽琼[1] 

机构地区：[1]云南省玉溪市人民医院新生儿科,玉溪653100

出　　处：《昆明医学院学报》2005年第1期85-87,共3页Journal of Kunming Medical College

摘　　要：目的 :探讨血清心肌酶谱活性检测在新生儿窒息时的临床应用价值 .方法 :对 192例窒息新生儿和 34例正常新生儿分别测定血清中谷草转氨酶 (AST) ,乳酸脱氢酶 (LDH) ,肌酸磷酸激酶 (CK)及肌酸磷酸激酶同工酶 (CK -MB)并进行资料分析 .结果 :窒息新生儿心肌酶异常 ,其程度与窒息轻重成正比 ,差异显著 (P <0. 0 1) .结论 :血清中CK -MB作为判断新生儿缺氧缺血性心肌损害的生化指标特异性较强 .Objective: To discuss the clinical values of detection of myocardial zymogram in serum during the asphyxia of neonate.Methods: The AST, LDH, CK and CK-MB of 192 suffocated neonates and 34 normal neonates were measured, and the measure data were analyzed.Results: The myocardial zymogram in serum of suffocated neonates was abnormal, especially CK-MB.And the abnormality increased as the degree of suffocation increased, compared with the normal group (P<0.01).Conclusion: K-MB in serum can be an index for the specific evaluation of anoxia and ischemia damage to myocardium.

关 键 词：血清心肌酶谱 新生儿窒息 CK-MB 窒息新生儿 临床意义 肌酸磷酸激酶同工酶 正常新生儿 结论 乳酸脱氢酶(LDH) 目的 

分 类 号：R722.12[医药卫生—儿科] R542[医药卫生—临床医学]