滨蒿炔类和黄酮类成分研究Ⅱ  

Acetylenes and Flavonoids from Artemisia scopariaⅡ

作　　者：谢韬[1] 刘净[1] 梁敬钰[1] 张志明[1] 魏秀丽[1] 

机构地区：[1]中国药科大学天然药物化学教研室,南京210009

出　　处：《中国天然药物》2005年第2期86-89,共4页

摘　　要：目的 :研究滨蒿ArtemisiascopariaWaldst etkit 化学成分 ,阐明其药理作用物质基础。方法 :薄层层析 ,硅胶反复柱层析 ,波谱分析技术和理化常数对照。结果 :从 80 %乙醇提取物中分离并鉴定了 12个化合物 ,分别是Capillone(1)、Capillin(2 )、5 ,7,4′ 三羟基-6 ,3′-二甲氧基黄酮 (Jaceosidin ,3)、柯伊利素 (Chrysoeriol,4 )、茵陈黄酮 (Arcapillin,5 )、木犀草素 (Luteolin ,6 ) ,柯伊利素-7-O-β-D 吡喃葡萄糖苷 (Chrysoeriol-7-O-β-D glucopyra noside,7)、仙人掌苷 (Cacticin ,8)、异鼠李黄素-3-O-β- D 吡喃葡萄糖苷 (Isorhamnetin 3 O β D glucopyranoside ,9)、槲皮素-7-O-α- L- 吡喃鼠李糖苷 (Quercetin-7-O-α- L- rhamnopyranoside ,10 )、金丝桃苷 (Hyperin ,11)、正丁基-β- D-吡喃果糖苷 (n butyl-β- D fructopyranoside,12 )。结论 :化合物 1、3、4、6、7、9、10。AIM:To study the chemical constituents of Artemisia scoparia Waldst.et kit.METHOD:The chemical constituents were isolated by using repeated silical gel column chromatography,and their structures were elucidated on the basis of spectral analysis.RESULT:12 compounds have been isolated from this plant,and the structures of chem have been identified as Capillone(1),Capillin(2),Jaceosidin(3),Chrysoeriol(4),Arcapillin(5),Luteolin(6),Chrysoeriol-7-O-β-D-glucopyranoside(7),Cacticin(8),Isorhamnetin-3-O-β-D-glucopyranoside(9),Quercetin-7-O-α-L-rhamnopyranoside(10),Hyperin(11),n-butyl-β-D-fructopyranoside(12).CONCLUSION:Compounds1,3,4,6,7,9,10 and 12 have been isolated from this plant for the first time.

关 键 词：滨蒿炔类 黄酮类 中药材 化学成分 结构鉴定 波谱分析技术 

分 类 号：R282.71[医药卫生—中药学] R284[医药卫生—中医学]