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机构地区:[1]山东省青岛市妇女儿童医疗保健中心,山东青岛266011 [2]山东省青岛大学医学院儿科教研室,山东青岛266011
出 处:《医学临床研究》2004年第8期845-847,共3页Journal of Clinical Research
摘 要:【目的】通过对 1993年 7月至 2 0 0 3年 6月转入本院新生儿科的极低出生体重儿 (VLBWI)进行统计并进行前后 5年的比较 ,评价VLBWI这一生命脆弱的特殊群体的收治情况及并发症变迁。【方法】回顾性分析近 10年NICU收住的 187例极低出生体重儿的临床资料。【结果】发现 1998年 7月至 2 0 0 3年 6月 (后 5年 )出生的VLBWI胎龄、出生体重较 1993年 7月至 1998年 6月 (前 5年 )降低 ,平均住院天数延长 (t值分别为 3.2 ,2 .9,1.97,均P <0 .0 5 ) ,后 5年中第三季度收入院的VLBWI较前明显增多 (χ2 =7.4 ,P <0 .0 5 ) ,在Ⅲ级医院出生的VLBWI较前减少 (χ2 =4 .78,P <0 .0 5 ) ,在Ⅱ级医院出生的VLBWI较前增多 (χ2 =6 .0 1,P<0 .0 5 ) ,VLBWI合并症中新生儿窒息与肺透明膜病的发病率较前升高 (χ2 分别为 6 .6和 6 .9,P <0 .0 5 )。VLBWI中存在围产期异常及其母存在妊娠合并症的发生率较前增多 (χ2 分别为 8.3和 4 .37,P <0 .0 5 )。【结论】由于抢救技术的提高 ,极低出生体重儿呈低龄、小体重、住院日延长趋势 ,在Ⅱ级医院出生者增多 ,围产期异常的发生并未相应下降 ,死亡风险及救治代价较前增加 ,应予重视。Objective To evaluate the enrollment, treatment and changes of complication in very low birth weight infants (VLBWI) transferred into neonate intensive care unit (NICU) from July,1993 to June,2003 and compare the data of first 5 years with those of second 5 years.The clinical data of 187 VLBWI admitted in NICU during recent 10 years were analyzed retrospectively.The embryo age and birth body weight in VLBWI born from July,1998 to June 2003(second 5 years) decreased as compared to those born from July,1993 to June,1998 (first 5 year), with a prolonged average duration of hospitalization (t= 3.2, 2.9 ,1.97,P<0.05). The number of neonates enrolled in the third quarter of the late 5 years increased over before (χ 2=7.4,P<0.05). The VLBWI born in the third grade hospitals decreased over before(χ 2=4.78,P<0.05), whereas those born in the second grade hospitals increased(χ 2=6.01,P<0.05).As for the complications found in VLBWI, the incidence of asphyxia and neonatal respiratory distress syndrome(NRDS) raised (χ 2=6.6 and 6.9 respectively, P<0.05); while the occurrence rate of perinatal abnormity in VLBWI and pregnancy complication happened to their mothers also increased(χ 2 =8.3 and 4.37 respectively,P<0.05).[Conclusion]With the improvement of rescue technique, embryo age and birth weight of VLBWI become smaller and lower, the duration of hospital stay shows a longer tendency. The VLBWI born in the second grade hospital increase, but the incidence of perinatal abnormity does not decline, with the death risk and rescue cost increasing over before. Therefore, serious attention should be paid to these problems.
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