胰岛素泵治疗2型糖尿病疗效研究  

作　　者：娄宁[1] 王文汇[1] 崔莹[1] 

机构地区：[1]山东大学临床医学院暨济南市中心医院,山东济南250013

出　　处：《山东医药》2005年第7期9-10,共2页Shandong Medical Journal

摘　　要：目的　观察胰岛素泵连续皮下注射胰岛素(CSII)治疗2型糖尿病、减少低血糖反应、改善生活质量的效果。方法　对血糖控制不良,需要住院使用或调整胰岛素治疗的2型糖尿病2 6例患者,随机分为CSII组(12例)和常规多次皮下注射胰岛素(MSII)组(14例)进行强化胰岛素治疗。结果　两组均达到目标血糖值,但CSII组血糖控制时间显著少于MSII组(P<0 .0 5 ) ,且胰岛素用量少于MSII组,低血糖发生率较低,能较有效地控制黎明现象发生。结论　胰岛素泵治疗糖尿病快速、安全、方便,是难治性2型糖尿病患者理想的强化治疗方案。Objective To study the effect of continuous subcuta neous insulin infusion(CSI I) to type 2 diabetes mellitus on controlling hyperglycemia,reducing hypoglyce mia occurrence and improving quality of life.Methods 26 poorly controlled type 2 diabe tic patients were studied by two methods of intensive insulin delivery:CSII gro up (n=12) and multiple subcutaneous insulin injection(MSII) group (n=14). Results Both groups reached the target BGs,but the average dura tions of CSII was shorter (P<0.05);the hypoglycemia incidence in CSII was less and the dawn phenomenon was controlled better.Conclusion Insulin pumping therapy is a safe,effective therapeutic method as an in tensive care.

关 键 词：2型糖尿病 胰岛素泵 连续皮下注射 胰岛素 血糖控制 

分 类 号：R587.1[医药卫生—内分泌] R977.15[医药卫生—内科学]