Functional brain laterality for sequential movements:Impact of transient practice  

作　　者：ZHUYihong DONGZongwang WENGXuchu CHENYizhang 

机构地区：[1]MedicalSchool,ZhejiangUniversity,Hangzhou310006,China [2]DepartmentofPsychology,SchoolofEducation,HebelNormalUniversity,Shijiazhuang050091,China//LaboratoryforHigherBrainFunction,InstituteofPsychology,ChineseAcademyofSciences,Beijing100101,China [3]MedicalSchool,ZhejiangUniversity,Hangzhou310006,China//LaboratoryforHigherBrainFunction,InstituteofPsychology,ChineseAcademyofSciences,Beijing100101,China [4]MedicalSchool,ZhejiangUniversity,Hangzhou310006China//InstituteotNeuroscience,SecondMilitaryMedicalUniversity,Shanghai200433,China

出　　处：《Chinese Science Bulletin》2005年第3期235-239,共5页

基　　金：This work was supported by the National Natural Science Foundation of China(Grant Nos.30425008,30128005,and 30170325);the National Basic Research Program of China(Grant No.G1999054000);the Health Bureau of Zhejiang Province(Grant No.2002B019).

摘　　要：The impact of learning on brain functional laterality has not been systematically investigated. We em- ployed an event-related functional magnetic resonance im- aging combined with a delayed sequential movement task to investigate brain activation pattern and laterality during a transient practice in 12 subjects. Both hemispheres, involving motor areas and posterior parietal cortex, were engaged during motor preparation and execution, with larger activa- tion volume in the left hemisphere than in the right. Activa- tion volume in these regions significantly decreased after a transient practice, with more reduction in the right hemi- sphere resulting increase in left lateralization. The theoretical implications of these findings are discussed in relation to the physiological significance of brain functional laterality.The impact of learning on brain functional laterality has not been systematically investigated. We employed an event-related functional magnetic resonance imaging combined with a delayed sequential movement task to investigate brain activation pattern and laterality during a transient practice in 12 subjects. Both hemispheres, involving motor areas and posterior parietal cortex, were engaged during motor preparation and execution, with larger activation volume in the left hemisphere than in the right. Activation volume in these regions significantly decreased after a transient practice, with more reduction in the right hemisphere resulting increase in left lateralization. The theoretical implications of these findings are discussed in relation to the physiological significance of brain functional laterality.

关 键 词：脑 连续运动系统 功能磁性图象 生理学 数据分析系统 

分 类 号：R338.2[医药卫生—人体生理学]