鸡血藤有效成分研究  

Studies on the active constituents in vine stem of Spatholobus suberectus

作　　者：崔艳君[1] 刘屏[2] 陈若芸[1] 

机构地区：[1]中国医学科学院中国协和医科大学药物研究所,北京100050 [2]中国人民解放军总医院,北京100853

出　　处：《中国中药杂志》2005年第2期121-123,共3页China Journal of Chinese Materia Medica

基　　金：国家自然科学基金资助项目 (3 0 0 70 890 )

摘　　要：目的 :研究鸡血藤原植物密花豆Spatholobussuberectus的有效成分。方法 :利用各种色谱技术进行分离纯化 ,根据理化性质和各种波谱技术进行结构鉴定。结果 :分离鉴定了 8个化合物 ,分别为芒柄花苷 (ononin ,1) ,樱黄素 (prunetin ,2 ) ,没食子儿茶素 (gallocatechin ,3) ,儿茶素 (catechin ,4 ) ,表儿茶素 (epicatechin ,5 ) ,丁香酸 (syringicacid ,6 ) ,香草酸 (vanillicacid ,7) ,胡萝卜苷 (daucosterol,8)。结论 :化合物 3,4 ,6 ,7为首次从密花豆属中分离得到。其中化合物Objective: To study the active constituents in vine stem of Spatholobus suberectus. Method: The constituents of Spatholobus suberectus were systematically separated with various chromatographic techniques. The structures were elucidated by physico-chemical properties and spectral data. Result: Eight compounds were isolated from S. suberectus, and were identified as: ononin (1), pruneitin (2), gallocatechin (3), catechin (4), epicatechin (5), syringic acid(6), vanillic acid(7) and daucosterol(8). Conclusion: Compound 3,4,6,7 were obtained from Spatholobus genus for the first time. Compound 4 has stimulation to proliferation of hematopoietic progenitor cell.

关 键 词：鸡血藤 有效成分 表儿茶素 胡萝卜苷 首次 骨髓抑制 造血祖细胞 分离鉴定 利用 理化性质 

分 类 号：R284.1[医药卫生—中药学] R282.71[医药卫生—中医学]