马鞭草化学成分的研究  

Studies on the chemical constitutents in herb of Verbena officinalis

作　　者：田菁[1] 赵毅民[1] 栾新慧[1] 

机构地区：[1]军事医学科学院毒物药物研究所,北京100850

出　　处：《中国中药杂志》2005年第4期268-269,共2页China Journal of Chinese Materia Medica

摘　　要：　目的:分离鉴定马鞭草的化学成分。方法:乙醇提取,大孔树脂、硅胶、聚酰胺柱色谱分离,所得单体成分通过UV,IR,NMR及MS波谱分析确定结构。结果:分得4个化合物,分别鉴定为芹菜素(Ⅰ), 4′-羟基汉黄芩素(Ⅱ),马鞭草苷(Ⅲ),戟叶马鞭草苷(Ⅳ)。结论:化合物Ⅰ,Ⅱ为首次从该属植物中分离得到。Objective: To isolate and identify the chemical constituents from Verbena officinalis. Method: The compounds were isolated by means of chromatography and the structures were determined on the basis of physical and spectral analysis. Result: Four compounds were isolated and identified as apigenin(Ⅰ), 4′-hydroxywogonin(Ⅱ), verbenalin(Ⅲ) and hastatoside(Ⅳ). Conclusion: Compounds Ⅰ and Ⅱ were obtained from the genus for the first time.

关 键 词：马鞭草 化学成分 汉黄芩素 首次 乙醇提取 芹菜素 MS 分离鉴定 单体成分 植物 

分 类 号：R284.1[医药卫生—中药学] R282[医药卫生—中医学]