成年人肺结核病的非生物危险因素病例对照研究  

Nonbiologic risk factors of pulmonary tuberculosis among adults in Henan: A case-control study

作　　者：王国杰[1] Adrian Sleigh 周刚[1] Sukhan Jackson 刘禧礼[1] 

机构地区：[1]河南省疾病预防控制中心,郑州450003 [2]National Center for Epidemiology and Population Health,the Australian National University [3]School of Economics,the University of Queensland

出　　处：《中华流行病学杂志》2005年第2期92-96,共5页Chinese Journal of Epidemiology

基　　金：UNDP WB WHOTDR资助项目 (ID :A10 166) ;河南省科技发展计划国际科技合作资助项目 (ID :0 3 4664 0 0 4)

摘　　要：目的　探讨影响成年人患肺结核病的非生物危险因素。方法　采用 1∶2配比病例对照研究 ,选取 15 8例 2 5～ 6 0岁的涂阳肺结核病患者作为病例组 ,每个病例选取 2名与其住所相邻、同性别、同年龄组的正常人作为对照 ;制定统一的调查表进行入户调查 ;采用单因素和多因素条件logistic回归进行统计分析。结果　单因素分析有统计学意义 (P <0 .0 5 )的变量有婚姻状况、文化程度、个体经营、吸烟、外出打工史、家庭年收入、家庭收入在社区的水平、家庭财产 ;多因素分析进入模型的有统计学意义 (P <0 .0 5 )的变量为婚姻状况、个体经营、吸烟、家庭财产、外出打工史 ,其OR值分别为2 .82 6、2 .35 0、1.5 36、0 .70 7、2 .0 96。结论　单身、吸烟、个体经营、有外出打工史是肺结核病的危险因素 ,家庭经济条件好是肺结核病的保护因素 ;在结核病控制工作实践中 ,采取相应的针对性措施有助于结核病的疫情控制。Objective To study the nonbiologic risk factors of tuberculosis (TB) among adults. Methods 1∶2 matched case-control study was conducted. 158 new smear positive pulmonary TB patients with 25-60 years of age were notified and registered from three county anti-TB institutions in Henan from October 2002-March 2004,were selected as cases. Two healthy persons were selected to match each case,with the same sex and age group, from the nearest neighbors of the case as controls. Interview was carried out with a uniform designed questionnaire at the residence of the object. Univariate and multivariate condition logistic regression models were used. Results The results of univariate analysis showed that marital status,education,self-employed occupation,smoking,out-migration for work away from hometown,household annual income level and household property were significantly associated with TB prevalence ( P <0.05 ); multivariate analysis showed that marital status,self-employed occupation,smoking, household economic condition and out-migration for work, away from home were also associated with TB ( P < 0.05 ),and OR values were 2.826 , 2.350 , 1.536 , 0.707 , 2.096 ,respectively.Conclusion Being single,smoking,self-employed occupation and out-migration for work were nonbiologic risk factors of TB while good household economic condition was a protective factor.

关 键 词：肺结核病 危险因素 吸烟 成年人 病例对照研究 结核病控制 OR值 生物 家庭经济条件 针对性 

分 类 号：R521[医药卫生—内科学] G633[医药卫生—临床医学]