三例家族性高胆固醇血症患者动脉血管超声检查随访  

The Ultrasonic Study of Blood Vessels in Patients with Familial Hypercholesterolemia

作　　者：勇强[1] 孙慧[1] 李治安[1] 王绿娅[2] 蔺洁[2] 

机构地区：[1]首都医科大学附属北京安贞医院超声诊断科,北京100029 [2]首都医科大学附属北京安贞医院心肺血管疾病研究所动脉硬化研究室,北京100029

出　　处：《中国医师杂志》2005年第2期200-202,共3页Journal of Chinese Physician

基　　金：北京市自然科学基金 (70 32 0 1 2 );首都医科大学基础临床合作基金 (0 2JL1 9) ;北京市科技新星计划资助项目 (2 0 0 4B2 7)

摘　　要：目的　探讨家族性高胆固醇血症 (FH)的腹部及外周动脉血管动态的变化。方法　对 3个FH家系中 3名子女 (先证者 )进行血管超声检查 ,观察动脉内 -中膜厚度 (IMT)、管腔狭窄程度、血液动力学改变、有无斑块以及斑块数量。结果　 3名FH患者的颈动脉斑块较前增多 ,颈总动脉、股总动脉IMT亦明显增厚 ,而锁骨下动脉、椎动脉、腹主动脉、肾动脉、髂动脉、月国动脉治疗前后均未见明显内膜增厚。结论　无创伤性血管超声检查可以作为观察FH血管改变的首选影像学的随访方法。Objective To explore the dynamic changes of abdominal and peripheral arteries in the patients with familial hypercholesterolemia(FH). Methods The intima-media thickness(IMT), stenotic degree and hemodynamics change of arteries were measured by ultrasonography in three children in 3 FH pedigrees. Results The plaques number and IMT of carotid and femoral arteries in the patients with FH significantly increased. The IMT of vertebral artery, subclavein artery, abdominal aorta, renal artery, illac artery and popliteal artery did not obviously changed. Conclusion Noninvasive vascular ultrasound was a preferred imaging technique to follow up the vascular change in the patients with FH.

关 键 词：家族性高胆固醇血症 患者 动脉血管 随访 FH IMT 血管超声 结论 子女 方法 

分 类 号：R445.1[医药卫生—影像医学与核医学]