血管内皮细胞与平滑肌细胞间的信息传递  

Intercellular Informational Communication Between Vascular Endothelial Cells and Smooth Muscle Cells

作　　者：范平[1] 司军强[1] 张志琴[1] 

机构地区：[1]石河子大学医学院医学系,新疆石河子832002

出　　处：《石河子大学学报（自然科学版）》2004年第6期550-553,共4页Journal of Shihezi University(Natural Science)

基　　金：国家自然科学基金资助项目(30460043)

摘　　要：血管内皮细胞和血管平滑肌细胞之间存在着肌内皮间缝隙连接,进行电和化学的信息传递,以协调血管的舒缩活动。电信号可以从内皮细胞到平滑肌细胞进行传递,相反,也可以从平滑肌细胞到内皮细胞进行传递。内皮源性超极化因子、乙酰胆碱、缓激肽、第二信使等物质亦可引起内皮细胞或/和平滑肌细胞细胞膜的超极化或去极化,参与血管内皮细胞与平滑肌细胞间的信息传递。The electrical and chemical signals are transmitted through the myoendothelial gap junctions which exist between the vascular endothelial cells(VEC) and the vascular smooth muscle cells(VSMC) in order to coordinate vasomotor activities.Electrical signals may propagate from VEC to VSMC,in contrast, electrical signals may propagate from VSMC to VEC. The cellular membrane potential hyperpolarization or depolarization is caused by some merterrials(such as endothelium-derived hyperpolarizing factor, acetylcholine, bradykinin, intercellular second messager and so on) which take part in the informational communication between VEC and VSMC.

关 键 词：血管平滑肌细胞 血管内皮细胞 超极化 缓激肽 缝隙连接 乙酰胆碱 第二信使 信息传递 化学 参与 

分 类 号：S436.5[农业科学—农业昆虫与害虫防治] G633[农业科学—植物保护]