沙眼衣原体感染后大鼠卵巢S-100阳性树突状细胞的变化  

Variations of S-100 Positive Dendritic Cells in Ovary Corpus Luteum Following Chlamydial infection

作　　者：黄海玲[1] 王燕舞[1] 孟运莲[1] 

机构地区：[1]武汉大学医学院组织学与胚胎学教研室

出　　处：《解剖科学进展》2005年第1期10-11,15,共3页Progress of Anatomical Sciences

摘　　要：目的　研究沙眼衣原体(CT)感染后,大鼠卵巢树突状细胞(DC)的变化。方法　成年Wistar雌 性大鼠,单侧卵巢囊接种沙眼衣原体E型株,于感染第1/2d、7d、14d取材,用免疫组化方法检测大鼠卵巢 DC的变化。结果　CT感染后大鼠卵巢黄体内S 100+阳性DC平均光密度值明显高于对照组(P<0.05或 0.01)。结论　沙眼衣原体感染可引起大鼠卵巢黄体内S 100阳性DC的表达。Objective To study the variations of S-100 positive dendritic cells(DC) in ovary following chlamydial infections. Methods Female Wistar rats were inoculated with chlamydial trachomatis immunotype E into the ovarian bursa. The rats were killed at 1/2 day, 7th day, 14th day postinoculation respectively. The variations of positive DC in ovary was detected by immunohistochemistry. Results The average optic density of positive S-100 +DC in ovary corpus luteum in inoculation group was higher than that in control. Conclusion Chlamydial infection caused the overexpression of S-100 in dendritic cells of ovary corpus luteum in wistar rats.

关 键 词：大鼠 卵巢 阳性 S-100 沙眼衣原体感染 DC 树突状细胞 结论 取材 变化 

分 类 号：Q492[生物学—生理学] R711[医药卫生—妇产科学]