Separation of picolines by dissociation extraction  

甲基吡啶的解离萃取分离实验研究(英文)

作　　者：赵欢[1] 肖国民[1] 吕建华[1] 

机构地区：[1]东南大学化学化工系,南京210096

出　　处：《Journal of Southeast University(English Edition)》2005年第1期68-72,共5页东南大学学报（英文版）

摘　　要：The separation of the by-product (The volume fraction of 3-picoline is 68.472 2% and 4-picoline 26. 517 6% .) in the synthesis of pyridine by dissociation extraction wasstudied. Six separation conditions of the dissociation extraction-the kind and the dosage ofextractant and organic solvent, the concentration of the extractant and separation temperature-wereinvestigated. Different levels of each factor were chosen to form an orthogonal test of six factorsand five levels. The results show that the volume ratio of 3-picoline and 4-picoline in organicphase is the highest when 24 mL picolines are separated at 0 t by 2. 0 mol/L p-toluenesulfonic andn-heptane whose dosages are 40 mL and 48 mL, respectively. The effect of the separation isconsiderably improved with repetition test. This process of dissociation extraction has commendablepotential for industrial exploitation.应用解离萃取分离合成吡啶产生的3 -甲基吡啶(3- MPD)与4 -甲基吡啶(4- MPD)的混合物(φ(3- MPD)=68. 472 2%;φ(4- MPD)=26. 517 6% ),对影响解离萃取分离的6个因素萃取剂、萃取剂的浓度及投料量、有机溶剂及投料量,以及分离温度进行了研究.选取了各因素的不同水平进行了六因素五水平的正交试验,以有机相两甲基吡啶的体积比为主要考查对象,筛选出了解离萃取分离甲基吡啶混合物的最佳工艺条件:当甲基吡啶的混合物为24mL时,以浓度为2mol/L的对甲基苯磺酸为萃取剂,用量为40mL,正庚烷为溶剂,用量为48mL,温度为0℃时分离效果最好.通过重复性实验,分离效果得到明显提高,说明此法具有工业化潜力.

关 键 词：3-PICOLINE 4-picoline SEPARATION dissociation extraction orthogonal test 

分 类 号：TQ028.8[化学工程]