2型糖尿病患者生活质量量表的研制与考评  

Development and evaluation of quality of life scale for patients with Type 2 diabetes mellitus

作　　者：王乐三[1] 孙振球[1] 蔡太生[2] 周智广[3] 

机构地区：[1]中南大学公共卫生学院流行病与卫生统计学系,长沙410078 [2]中南大学湘雅二医院临床心理学研究中心,长沙410011 [3]中南大学湘雅二医院代谢内分泌研究所,长沙410011

出　　处：《中南大学学报（医学版）》2005年第1期21-27,共7页Journal of Central South University ：Medical Science

基　　金：国家"十五"科技攻关项目(2001BA702B05)

摘　　要：目的:编制适合我国2型糖尿病患者的生活质量量表。方法:根据WHO对生活质量的定义,采取结 构化的决策方法从多维度筛选指标构建2型糖尿病人生活质量量表DMQLS(qualityoflifescaleforpatientswith Type2diabetesmellitus)。应用DMQLS对236名2型糖尿病患者进行测试。结果:研制出由疾病、生理、社会、心 理、满意度5个维度共87个条目的DMQLS,其中疾病维度形成2型糖尿病患者特异条目子量表,生理、社会、心理、 满意度4个维度形成正常成年人群共性条目子量表。DMQLS1周重测信度为0.996,Cronbach’sα系数为0.969, 分半信度系数为0.879。因子分析提取21个公因子。DMQLS总分与SF 36总分的相关系数为0.763,普适子量表 与SF 36总分的相关系数为0.762;DMQLS总分与糖尿病特异性量表(DQOL)总分的相关系数为0.658,疾病维度 与DQOL总得分的相关系数为0.615。病情程度不同的患者DMQLS总分有差别,患者治疗前后DMQLS总分有差 别。结论:DMQLS是可靠、有效、灵敏的,可应用于2型糖尿病患者的生活质量评价。Objective To develop a specific quality of life scale for Chinese Type 2 diabetes mellitus (DM) patients. Methods According to the quality of life definition of WHO, we used methods adhered to the rigorous guidelines of instrument development in item pool formation, item selection and scale validation with the data of 236 Type 2 diabetic patients recruited. Results An 87-item Quality of Life Scale for patients with Type 2 DM-prior test version (DMQLS), including 5 domains (disease, physical, social, psychological, and satisfaction) was developed and showed good reliability and validity. The disease domain made up of Type 2 diabetes mellitus -specific sub-scale and the other 4 domains formed the generic sub-scale for adults. The test-retest correlation coefficient, Cronbach′s Alpha coefficient and split-half reliability coefficient of DMQLS were 0.996,0.969 and 0.879,respectively. Twenty-one common factors were extracted according to the conceptual model. The scale’s correlations with SF-36 and Diabetes Quality of Life Measure (DQOL) were 0.763 and 0.658. DMQLS could discriminate among those with different quality of lives. Conclusion DMQLS is reliable, valid and sensitive, and can be used to evaluate the curative effect of Type 2 diabetic patients.

关 键 词：2型糖尿病 生活质量量表 研制 考评 

分 类 号：R587.1[医药卫生—内分泌]