大孔吸附树脂富集雷公藤内酯醇的研究  

Study on macroporous adsorbing resin for purification of triptolide

作　　者：王曙东[1] 滕英博[1] 谢虞昇[1] 李克[2] 

机构地区：[1]南京军区南京总医院制剂科,江苏南京210002 [2]南京军区南京总医院检验科,江苏南京210002

出　　处：《医学研究生学报》2005年第3期204-205,共2页Journal of Medical Postgraduates

摘　　要：　目的:应用大孔吸附树脂D101型分离、纯化雷公藤内酯醇。　方法:用醇提水沉后,经D101树脂吸附及氧化铝柱除杂,用 95%乙醇解吸,高压液相色谱(HPLC)测定含量。　结果:雷公藤内酯醇可得到较好的保留。　结论:D101可应用于雷公藤内酯醇的富集。Objective: To apply D101 macroporous resin for separation and purification of triptolide. Methods: After extracted by alcohol the extracts were dissolved in water and passed through a macroporous resin column and a aluminum oxide column. Then the triptolide on the columns were eluated with 95% alcohol and determination by HPLC. Results:Triptolide could be retained on D101 column. Conclusion: D101 resin can be used to refine the triptolide.

关 键 词：雷公藤内酯醇 大孔吸附树脂 高效液相色谱法 

分 类 号：R284.2[医药卫生—中药学]