血液凝固过程中粘度动态变化的测量方法及其临床意义的研究  

Research of Measurement for Blood Plasma Viscosity in the Process of Blood Concreting and Its Clinical Significance

作　　者：徐圣普[1] 周炜[1] 赵金城[1] 边自朋[1] 

机构地区：[1]中国医学科学院生物医学工程研究所,天津300192

出　　处：《生物医学工程研究》2004年第1期31-33,共3页Journal Of Biomedical Engineering Research

摘　　要：探讨血液凝固过程中一种测量血液粘度动态变化的方法。设计的锥板粘度计由产生不同切变率的机械传动装置、放置血样的试样杯和锥板等装置组成。用 80 5 1单片机设计了PID检测控制系统 ,检测到的扭矩反映了血液粘度的变化。用此装置检测了鸡、兔、大鼠、及人的离体血液凝血过程中有物理性质改变的粘度指标 ,随时间变化的动态曲线及特征参数 ,表明此法可行、有效。分析在不同病理状态下的这些曲线和特征参数变化规律 ,有助于预报与防治血栓病 。A measurement method of blood plasma viscosity in the process of blood concreting was researched.The viscometer was composed of mechanical rotating parts creating different shear rate, a sample cup and a cone plank. Using 8051 microcomputer,a PID controlling measurement system was developped and the torque was related to viscosity in the measurement. The changing rules of viscosity related to time and the parameters that influenced the blood coagulation in plasma samples of chicken, rabbit, rat and human were measured. The results show that the method is efficient and supply useful information for clinical research.

关 键 词：血液凝固 血液粘度 临床意义 血栓病 治血 动态变化 凝血 装置组成 动态曲线 离体 

分 类 号：Q941[生物学—植物学] R446[医药卫生—诊断学]