次声对豚鼠听阈影响的实验研究  

Auditory Threshold After Infrasound Exposure in Guinea Pig

作　　者：刘淑芳[1] 杜宝东[1] 刘莉[1] 姬柏春[1] 

机构地区：[1]吉林大学第一医院耳鼻咽喉-头颈外科,长春130021

出　　处：《听力学及言语疾病杂志》2005年第2期110-111,114,共3页Journal of Audiology and Speech Pathology

基　　金：国家自然科学基金资助项目 (编号 3 9770 64 1)

摘　　要：目的　探讨不同强度次声暴露下豚鼠听阈的变化。方法　采用面神经管长期置入电极方法 ,测试不同强度、不同时间的次声暴露下 2 0只清醒豚鼠的听阈变化 ,并将暂时阈移 (temporarythresholdshifting ,TTS)与永久阈移 (permanentthresholdshifting ,PTS)的指标进行系统分析。结果　 8Hz的次声在 130dBSPL暴露 30小时即可引起PTS ,而在 12 0dBSPL暴露 30小时对听阈的影响不大 ,可引起TTS。结论　在强度≥ 130dBSPL次声暴露 30小时可引起豚鼠耳蜗功能的永久性损害 ,造成PTS。Objective The auditory threshold was measured after infrasound exposure and the index of temporary thre- sh old s hift ing (TTS) and permanent threshold shifting (PTS) was analysed in guinea pigs. Methods The electrode was inserted into Fallopian's canal of guinea pigs for long-term study.The auditory threshold in awake guinea pigs exposed to infrasound with various time and intensity was observed systematically. Results The PTS was caused after 8 Hz 130 dB SPL infrasou nd exposure and TTS was caused after 120 dB SPL in 30 hours. Conclusion The cochlea function was damaged permanently after 130 dB SPL infrasound exposure.

关 键 词：次声 暴露 听阈 暂时性阈移 永久性阈移 

分 类 号：R764.433[医药卫生—耳鼻咽喉科]