紫外光聚合法制备L-DBTA手性分子印迹聚合物的研究 Ⅰ.紫外光聚合制备条件  

Study on the Molecular Imprinted Polymers with Recognition Properties Towards to Dibenzoyl-L-tartaric Acid Prepared by Photo-Polymerization Method Ⅰ. Photo-polymerization Conditions

作　　者：杨座国[1] 许振良[1] 

机构地区：[1]华东理工大学化学工程研究所,上海200237

出　　处：《功能高分子学报》2005年第1期36-41,共6页Journal of Functional Polymers

基　　金：国家重点基础研究发展计划(973计划)资助(2003CB615705)

摘　　要：以丙烯酸为功能单体,二苯甲酰 L 酒石酸(L DBTA)为模板分子,三羟甲基丙烷三丙烯酸酯(TMPTA)为交联剂,采用光聚合方法合成了 L DBTA手性分子印迹聚合物,讨论了功能单体种类、功能单体用量、交联剂用量、引发剂用量、三乙胺用量、光聚合温度、光聚合时间、光强度等对L DBTA手性分子印迹聚合物合成的影响。通过L DBTA手性分子印迹聚合物对底物的结合实验分析,表明手性分子印迹聚合物对L DBTA具有很好的识别性, L DBTA的选择性比二苯甲酰 D 酒石酸(D DBTA)高,其分离因子可达5.41。Using a functional monomer(methyl methacrylate, acrylamide, ethyl acrylate or acrylic acid) and a crosslinker(TMPTA), molecularly imprinted polymers(MIPs) with recognition properties to dibenzoyl-L-tartaric acid(L-DBTA) were prepared by photopo-polymerization method in the presence of a template(L-DBTA) in acetonitrile solution.The experimental results indicated that the MIPs had higher L-DBTA binding ability than D-DBTA′s and also higher than corresponding non-imprinted polymers. The binding ability of MIPs is the highest at template (n_(L-DBTA)/n_(AA)/n_(TMPTA)= 1/4/12 as photo-polymerization time was 1.5h and photopolymering in a ice-water bath under a 100W ultraviolet lamp about 0.07m. Based on the optimal experimental results, it was found that the highest separation factor (α) of L-DBTA/D-DBTA of the MIPs could reach to be 5.41.

关 键 词：紫外光聚合法 L-DBTA 分子印迹技术 聚合物 手性识别 阻聚剂 二苯甲酰酒石酸 

分 类 号：O631[理学—高分子化学]