灌注超声导管与冷盐水灌注射频导管电学隔离肺静脉的对比研究  

A comparative study on the efficacy of pulmonary veins isolation between irrigated ultrasound catheter and saline-irrigated ablation catheter

作　　者：秦小飞[1] 董建增[2] 龙德勇[2] 刘闯[1] 

机构地区：[1]郑州大学第一附属医院心内科,河南郑州450052 [2]首都医科大学附属安贞医院心内科,北京100029

出　　处：《河南医学研究》2005年第1期8-10,共3页Henan Medical Research

摘　　要：目的 :对比灌注超声导管与冷盐水灌注射频导管电学隔离犬肺静脉的效果 ,以探讨灌注超声导管用于肺静脉电学隔离治疗的可行性。方法 :健康杂种家犬 2 3只 ,按不同消融方法随机分为冷盐水灌注射频导管组 (A组 ,n =12 )及灌注超声导管组 (B组 ,n =11)。房间隔穿刺后在环状电极标测指导下分别采用两种导管行肺静脉电学隔离 ,隔离 3 0min后再次评价心房与肺静脉之间 (LA -PV)电传导是否恢复。结果 :A组与B组犬肺静脉电隔离即刻成功率分别为 97. 9% (4 6/ 47)和 78 .6% (3 3 / 42 ) ,B组显著低于A组 (P <0 . 0 5 ) ;3 0min后左心房 -肺静脉电学传导恢复率分别为 71 .7% (3 3 / 46)和 2 7 .3 % (9/ 3 3 ) ,B显著低于A组 (P <0 . 0 1)。结论 :灌注超声导管电学隔离肺静脉的即刻成功率低于冷盐水灌注射频导管 ;但隔离成功后 3 0minLA -PV电传导恢复率也显著低于冷盐水灌注射频导管。Objective: To investigate the differences in pulmonary veins isolation (PVI) between irrigated ultrasound catheter and saline_irrigated ablation catheter and the feasibility of irrigated ultrasound catheter's clinical applicationMethods: Pulmonary veins isolation were carried out in 23 healthy canines with saline-irrigated ablation catheter irrigated ultrasound catheter or under the guiding of circular mapping The animals were randomized into saline_irrigated ablation catheter group (Group A, n=12) or irrigated ultrasound catheter group (Group B, n=11) respectively Electrical conduction between left atrium and pulmonary veins(LA-PV) was revaluated 30 minutes after initial pulmonary veins isolationResults: Immediate success rate of PVI was 979%(46/47) in Group A and 786%(33/42) in Group B respectively, and success rate in group B is much lower than that in Group A (P<005) However, 30 minutes after initial isolation, electrical conduction between LV-PV was observed in 717%(33/46) of the canines from Group A and 273%(9/33) of the canines from Group B, and the recurrence rate in Group B is lower than that in Group A(P<001) Conclusion: Though ccess rate lower su of PVI was observed with irrigated ultrasound catheter compared with saline_irrigated ablation catheter, the recurrence rate of LV-PV conduction is also lower

关 键 词：肺静脉 冷盐水 灌注 导管 超声 注射 射频 电学 结论 指导 

分 类 号：R541.75[医药卫生—心血管疾病] G633[医药卫生—内科学]