冠状动脉梗死相关病变钙化与临床表现的关系  

Relationship between calcification of culprit coronary artery lesions and clinical presentation

作　　者：惠波[1] 党群[2] 金喆[2] 夏大胜[2] 王小飞[2] 高陆[2] 蔡林[2] 张靖[2] 王佩显[1] 

机构地区：[1]天津医科大学总医院心内科 [2]天津市第一中心医院心内科

出　　处：《临床心血管病杂志》2005年第3期147-149,共3页Journal of Clinical Cardiology

摘　　要：目的:探讨冠状动脉梗死相关病变钙化与临床表现的关系。方法:将经血管内超声(IVUS)检查发现有冠状动脉钙化的患者48例分为两组:急性冠状动脉综合征(ACS)组 28 例、稳定型心绞痛(SAP)组 20 例。对两组患者的冠状动脉梗死相关病变钙化进行测量及分析。结果:ACS组患者血管梗死病变处较SAP组患者相对缺乏,钙化两组的最大钙化弧度分别为(85.48±71.52)°,(152.00±103.08)°, P<0.05。ACS组的钙化斑块比例低于SAP组,57.14%∶83.33%,P<0.05;前者偏心斑块多于后者,93.88%∶54.17%, P<0.01;破裂斑块亦多于后者,42.86%∶8.33%,P<0.01。结论:ACS患者血管梗死病变处较SAP患者相对缺乏钙化,这有助于对ACS发病机制的理解,钙化的存在也有助于识别冠状动脉狭窄病变。Objective:To explore the relationship between calcification of culprit coronary artery lesions and clinical presentation in patients with coronary heart disease(CHD). Method:Calcification of culprit coronary artery lesions in 48 patients with CHD were checked by intravascular ultrasound(IVUS). All patients were divided into two groups: acute coronary syndromes (ACS) (28 patients) and stable angina pectoris (SAP) (20 patients). Then we measured and analysed their calcification. Result: The maximal area of calcium in patients with ACS is less than SAP ( 85.48± 71.52°versus 152.00± 103.08°,P< 0.05).The calcium plaque in ACS patients is less than that in SAP patients ( 57.14% versus 83.33%, P< 0.05). The eccentric plaque ( 93.88% vesus 54.17%,P< 0.01) and plaque rupture ( 42.86% versus 8.33%,P< 0.01) of the former was more than those of the latter.Conclusion:IVUS detects calcification in 64.38% of coronary artery in patients with CHD. ACS is associated with the relative lack of calcium in the culprit lesions compared with lesions of patients with SAP. These findings will help us to understand the mechanism of ACS and to identify coronary lesions.

关 键 词：钙化 冠状动脉疾病 超声检查 血管内 

分 类 号：R336[医药卫生—人体生理学]