刺莓果复合制剂对小鼠学习记忆的促进作用  

Promoting action of compasotus Rosa davurica Pall preparation on learning and memiory in mice

作　　者：朴世浩[1] 张红英[1] 金长炼[1] 洪淳赞[1] 曲香芝[1] 吴祯久 金松哲[1] 

机构地区：[1]延边医学院药理学教研室,延边医学院环境卫生学研究室

出　　处：《延边医学院学报》1994年第2期123-126,共4页Journal of Medical Science Yanbian University

摘　　要：采用一次性被动回避条件反应—跳台法、水迷宫法的行为实验和３种化学药物所致记忆障碍的模型，观察了刺莓果复合制剂对小鼠学习记忆的影响．结果表明，刺莓果复合制剂明显对抗东莨菪碱所致记忆获得障碍，对氯霉素引起的记忆巩固不良和４００ｍｌ／Ｌ乙醇引起的记忆再现障碍亦均有拮抗作用．The effects of compasotus rosa davurica pall preparation(CRDPP ) on learning and memory were studied in mice by using one trial passive avoidance response. The results show that the CRDPP improves scopopamine-induced impairment of memory and chloram-phenical-induced disturbance of memorial retention, and presents an antagonistic action on 400mol/L alcohol-induced disturbance of memorial recall.

关 键 词：学习记忆 东莨菪碱 回避反应 小鼠 

分 类 号：R965.2[医药卫生—药理学]