婴幼儿轮状病毒腹泻危险因素的病例对照研究  

Case-control study on risk factors of rotavirus diarrhea among infants and children

作　　者：金辉[1] 王蓓[1] 沈惠 顾红英[3] 汪宁[1] 

机构地区：[1]东南大学公共卫生学院流行病学教研室,南京210009 [2]苏州市疾病控制中心 [3]苏州市儿童医院消化科

出　　处：《中国公共卫生》2004年第11期1302-1303,共2页Chinese Journal of Public Health

基　　金：国际疫苗研究所资助项目;东南大学科学基金资助项目(XJ0 1 90 0 1 )

摘　　要：目的　研究婴幼儿轮状病毒腹泻的影响因素。方法　按 1∶1配对原则 ,分别选取 74例社区对照和 6 3例医院对照进行多重病例对照研究。结果　母乳喂养期在 6个月以内的婴儿 (OR =0 14 7,95 %CI:0 0 2 8～ 0 76 4 )、住房的面积大 (OR =0 2 2 ,95 %CI:0 0 9～ 0 5 4 )感染轮状病毒的危险性较小 ;但 12个月后更长时间的母乳喂养 (OR=3 2 78,95 %CI:1 5 5 4～ 6 931)、母亲年龄较小 (OR =4 1 89,95 %CI:2 5 6～ 6 8 6 ;OR =12 77,95 %CI:1 5 8～10 3)、老人看护 (OR =11 39,95 %CI :2～ 6 5 31)、经常抱孩子外出 (OR =2 6 76 ,95 %CI:1 0 4 2～ 6 82 1)会增加轮状病毒腹泻的感染率。结论　母乳喂养在一定程度上可减少婴儿轮状病毒腹泻的发生 ,但喂养时间不宜过长 ;与外界环境接触机会增多 。Objective To discuss risk factors due to rotavirus diarrhea.Methods To select 63 hospital controls and 74 community controls which were matched cases for sex and age within one months in Suzhou were to analyze risk factors for rotavirus diarrhea.Results Breast-feeding before 6 months( OR =0 147,95% CI :0 028-0 764) and more area in housing( OR =0 22,95% CI :0 09-0 54)was protective factor,then breat-feeding after 12 month( OR =3 278,95% CI :1 554-6 931)did not decrease infective rate of rotavirus diarrhea;there was significance that younger mother( OR =41 89,95% CI :2 56-68 6; OR =12 77,95% CI :1 58-103),elder nursing( OR =11 39,95% CI :2-65 31) may be increase rotavirus diarrhea in the suburb and rural.Further,there was vulnerable to infect rotavirus diarrhea by going outside often( OR =2 676,95% CI :1 042-6 821).Conclusion At a certain extent breast-feeding may cut rotavirus diarrhea rate down,but there should not continue to feed too long.It may be the major risk factor that infants and children touch environment impurity.

关 键 词：轮状病毒 病例对照 危险因素 母乳喂养 

分 类 号：R725.1[医药卫生—儿科]