结节性甲状腺肿与淋巴细胞性甲状腺炎关系的探讨  

Relationship between nodular goiter and lymphocytic thyroiditis

作　　者：吕英志[1] 隋立荣[1] 廖松林[2] 

机构地区：[1]北京市第六医院病理科,北京100007 [2]北京大学医学部病理学系,北京100083

出　　处：《诊断病理学杂志》2004年第4期233-234,I061,共3页Chinese Journal of Diagnostic Pathology

摘　　要：目的　探讨结节性甲状腺肿与淋巴细胞性甲状腺炎伴发的意义。方法　收集 5 4 8例结节性甲状腺肿 ,35例甲状腺腺瘤 ,17例甲状腺癌 ,观察其伴淋巴细胞性甲状腺炎的发生率及病变特点。结果　结节性甲状腺肿伴淋巴细胞性甲状腺炎达 2 5 4 % (139/ 5 4 8) ,其中局灶性淋巴细胞性甲状腺炎占 2 4 3% (133/ 5 4 8) ,桥本甲状腺炎占1 1% (6 / 5 4 8)。甲状腺腺瘤无 1例伴发淋巴细胞性甲状腺炎 (0 / 35 )。甲状腺癌旁有局灶性淋巴细胞性甲状腺炎者 ,占 6 4 7% (11/ 17)。结论　结节性甲状腺肿伴淋巴细胞性甲状腺炎 ,特别是局灶性淋巴细胞性甲状腺炎伴发率较高 ,提示结节性甲状腺肿可能与自身免疫有一定关系 ;Objective To explore the significance of nodular goiter with lymphocytic thyroiditis. Methods 548 cases of nodular goiter, 35 cases of thyroid adenoma and 17 cases of thyroid carcinoma were collected. Their incidence rate and lesion features with lymphocytic thyroiditis were observed. Results Nodular goiters with lymphocytic thyroiditis were 25 4% (139/548), among which focal lymphocytic thyroiditis were 24 3% (133/548), Hosimoto's thyroiditis were 1 1% (6/548). Thyroid adenomas had no any case with lymphocytic thyroiditis (0/35), and thyroid carcinomas with focal lymphocytic thyroiditis were 64 7%. Conclusions The incidence of nodular goiter with lymphocytic thyroiditis, especially focal lymphocytic thyroiditis is higher,which indicate that nodular goiter may be relative to autoimmunization in some degree. Otherwise, whether focal lymphocytic thyroiditis exists or not, can be one of the points to distinguish adenoma from nodular goiter.

关 键 词：淋巴细胞性 桥本甲状腺炎 结节性甲状腺肿 局灶性 甲状腺腺瘤 甲状腺癌 自身免疫 发生率 观察 鉴别 

分 类 号：R581.4[医药卫生—内分泌] R733[医药卫生—内科学]