柴胡皂甙m和柴胡皂甙n的结构鉴定  

THE STRUCTURES OF SAIKOSAPONIN M ANDN FROM BUPLEURUM SMITHII WOLFF RY

作　　者：张如意[1] 陈喜奎[1] 杨宪斌[1] 谭利[1] 贺文义[1] 

机构地区：[1]北京医科大学药学院,中国医学科学院中国协和医科大学药物研究所

出　　处：《药学学报》1994年第9期684-688,共5页Acta Pharmaceutica Sinica

摘　　要：从黑柴胡（ＢｕｐｌｅｕｒｕｍｓｍｉｔｈｉｉＷｏｌｆｆ）根中分得二个新三萜皂甙。根据理化性质和波谱数据，分别鉴定为３β，２３，２８－三羟基齐墩果烷－１１，１３（１８）－二烯－３－Ｏ－β－Ｄ－吡喃葡萄糖基－（１→３）－β－Ｄ－吡喃呋糖甙，命名为柴胡皂甙ｍ（ｓａｉｋｏｓａｐｏｎｉｎｍ，ＩＶ），和３β，１６β，２３，２８－四羟基齐墩果烷－１１，１３（１８）－二烯－３－Ｏ－β－Ｄ－吡喃葡萄糖基－（１→６）－［α－Ｌ－吡喃鼠李糖基－（１→４）］－β－Ｄ－吡喃葡萄糖甙，命名为柴胡皂甙ｎ（ｓａｉｋｏｓ－ａｐｏｎｉｎｎ，ＩＸ）。From the roots of Bupleurum Smithii Wolff, collected in Minhe County,Qinghai,China,two new saikosaponins were isolated and their structures were elucidated on the basis of spectralanalysis of UV,IR,1HNMR,13CNMR and FAB-MS.The two new saponins named as saikosaponinm and saikosaponin n,were identified as 3 β,23,28-trihydroxyoleana-11,13(18)-dien-3-O-β-D-glu-copyranosyl-(1 →3)-β-D-fucopyranoside and 3β,16β,23,28-tetrahydroxyoleana-11, 13(18)-dien-3-O-β-D-glucopyranosyl-(1→6)-[α-L-rhamnopyranosyl(1→ 4)]-β-D-glucopyranoside,respectively.

关 键 词：黑柴胡 三萜 皂甙 柴胡 鉴定 

分 类 号：R284.1[医药卫生—中药学]