骨碱性磷酸酶检测在早期佝偻病诊断中的意义  

SIGNIFICANCE OF BONE ALKALINE PHOSPHATASE MEASUREMENT IN THE DIAGNOSIS OF RICKETS IN EARLY STAGE

作　　者：李馨[1] 

机构地区：[1]青岛大学医学院生物化学与分子生物学教研室,山东青岛266021

出　　处：《青岛大学医学院学报》2005年第1期76-77,共2页Acta Academiae Medicinae Qingdao Universitatis

摘　　要：①目的探讨骨碱性磷酸酶(BALP)在临床早期佝偻病诊断中的意义.②方法应用全血干化学免疫浓缩法检测48例临床表现疑似早期佝偻病幼儿血中BALP活性,并行X线检查.③结果 48例病儿中BALP＜200 U/L(正常)1例,200～250 U/L(可疑佝偻病)2例,＞250 U/L(临床佝偻病)45例;X线检查异常者40例,二者诊断符合率为88.9%.④结论血中BALP检测可用于早期佝偻病的诊断,值得在基层医院推广应用.Objective To study the significance of bone alkaline phosphatase(BALP) in diagnosis of early-stage rickets. Methods With the technique of whole blood dry chemistry, BALP activity of 48 young children with suspected early rickets was measured and X-rayed. Results <200 U/L one case(normal),200~250 U/L two cases(suspected rickets),>250 U/L 45 cases(clinical rickets); abnormal X-ray findings 40 cases.The consistent rate was 88.9%. Conclusion Blood BALP level may be used for the diagnosis of early-stage rickets, it is worth while to popularize in grass-roots hospitals.

关 键 词：骨 碱性磷酸酶 佝偻病 诊断 

分 类 号：R723[医药卫生—儿科]