多巴胺在2-氨基-5-巯基-[1,3,4]三氮唑自组装膜电极上的电化学行为研究  

The quasi-reversible response of dopamine at a self-assembled monolayers gold electrode modified with 2-amino-5-mercapto-triazole

作　　者：刘传银[1] 周享春[2] 李新民[1] 陆光汉[1] 

机构地区：[1]华中师范大学化学学院 [2]长江大学化学工程系湖北荆州,434023

出　　处：《华中师范大学学报（自然科学版）》2005年第1期74-78,共5页Journal of Central China Normal University：Natural Sciences

基　　金：湖北省教育厅重点资助项目(2003A010).

摘　　要：利用新合成的巯基试剂2 氨基 5 巯基 [1,3,4]三氮唑在金电极表面进行了首次自组装,用电化学法和扫描电子显微镜对自组装膜电极进行了表征.研究了多巴胺在该自组装膜电极上的电化学行为,发现该自组装膜能有效促进多巴胺在电极与溶液之间的电子传递,表现为一二电子传递的准可逆行为,电极反应速率常数为0.1049cm/s.该自组装膜电极用于多巴胺注射液含量的测定,结果满意.A newly synthesized reagent 2-amino-5-mercapto-triazole was used to fabricate self-assembled monolayers (SAMs) on gold for the first time. The SAMs modified electrode was characterized by electrochemical methods and scanning electronic microscopy (SEM). The electrochemical behaviors of dopamine were investigated at the SAMs electrode, the experimental results showed that the electrochemical oxidation of dopamine was a quasi-reversible and a two-electron transfer process, the constant of electrode reaction was 0.104 9 cm/s. The SAMs electrode has been used to determine the content of dopamine in drug injections with satisfactory results.

关 键 词：2-氨基-5-巯基-[1 3 4]三氮唑 多巴胺 自组装膜 准可逆响应 

分 类 号：O657.1[理学—分析化学]