早期综合干预对重度窒息患儿预后的影响  

Effects of early combined intervention for improving the prognosis of neonates with severe asphyxia

作　　者：明萌[1] 明星辰[2] 王大斌[1] 肖玉[1] 梁松[3] 

机构地区：[1]郧阳医学院附属太和医院儿科,湖北十堰442000 [2]郧阳医学院附属太和医院信息统计科,湖北十堰442000 [3]东风公司花果医院小儿弱智脑瘫治疗中心

出　　处：《郧阳医学院学报》2005年第1期12-14,共3页Journal of Yunyang Medical College

摘　　要：目的:探讨早期干预、丽珠赛乐和复方丹参多疗程治疗及康复治疗对改善重度窒息患儿预后的作用。方法: 70例重度窒息患儿分为干预组和对照组各 35例,干预组自新生儿期开始实施综合干预措施至 2岁。结果:干预组 1岁、2岁时智力发育指数(MDI)和心理运动发育指数 (PDI)均高于对照组,差异呈显著性 (P<0. 01);干预组的后遗症发生率为 8. 57%,对照组的后遗症发生率为 28. 57%,两组患儿预后之间的差异有显著性意义 (P<0. 05 )。结论:早期综合干预可促进重度窒息患儿智力发育,预防及降低神经系统后遗症的发生,明显改善重度窒息患儿的预后。Objective To investigate the effect of early intervention, lizhusaile and methanesulfonate therapy and physical therapy on improving the prognosis of neonates with severe asphyxia. Methods 70 cases of neonates with serious level of asphyxia were divided into 2 groups: 35 cases in intervention group and 35 cases in control group. Combined intervention was performed in intervention group from the birth to 2 years old.Results At the age of 1 and 2, the mental developmental index (MDI) and psycho-motor developmental index (PDI) in intervention group were significantly higher than those in control group(P<0.01); Also, the sequelae rate of intervention group was as low as 8.57% in comparison with 28.57% in control group(P<0.05). Conclusion Early combined intervention could promote the intellectual development of neonates with severe asphyxia, and, furthermore, it could decrease the incidence of nerve sequelae and improve prognosis.

关 键 词：早期综合干预 重度窒息 患儿 预后 心理运动发育指数 神经系统后遗症 综合干预措施 智力发育指数 对照组 早期干预 康复治疗 复方丹参 丽珠赛乐 新生儿期 显著性 发生率 多疗程 

分 类 号：R722.12[医药卫生—儿科]