海洋石油职工恶性肿瘤患者医院感染分析  

A analyse of nosocomial infection on the cases of malignant tumor in oil offshore staff

作　　者：张爱玲 赵崇瑜 欧宇春 周玲 朱小琴 

机构地区：[1]南海西部石油公司职工医院,广东省湛江524057

出　　处：《中华航海医学与高气压医学杂志》2005年第1期47-49,共3页Chinese Journal of Nautical Medicine and Hyperbaric Medicine

摘　　要：目的　探讨海洋石油职工恶性肿瘤患者并发医院感染的临床特点及防治方法。方法　采用回顾性病历分析法对我院近 5年收治的 75例海洋石油职工恶性肿瘤患者并发医院感染的基本情况,细菌培养结果及抗感染治疗的临床疗效等进行总结分析。结果　位于海洋石油职工癌谱前三位的肺癌、大肠癌、肝癌易并发医院感染,好发部位为呼吸道、消化道、口腔等,病原体以G-杆菌为主(55. 2% ),次之为继发于长期应用广谱抗菌素的真菌感染 (27. 6% ),且疗效差,死亡率高。结论　海洋石油职工恶性肿瘤患者医院感染的病原菌多为条件致病菌,对常用抗菌素耐药率高,肿瘤进展者治愈率低,预后差;积极控制原发病,合理应用抗菌素,方利于医院感染的防治。Objective To investigate the clinical characteristics, prevention and treatment of the malignant tumor patients with nosocomial infection in offshore staff.Methods 75 offshore staff cases with nosocomial infection and malignant tumors were analyzed. Results Nosocomial infections occurred mainly in patients with lung cancer,colorectal cancer and liver cancer. The respiratory tract was the most frequently infection site, followed by the gastric tract and the oral cavity .The most common pathogen was the Gram negative bacilli (55.2%).The second one was deep fungi (27.6%). The fungal infections always were found in the patients who had been treated with antibiotics for an extended period. In deep fungal infections,there is a low curative rate and a high mortality rate. Conclusions The conditioned pathogenic bacteria were the main pathogens in nosocomial infection with malignant tumors in offshore staff and most of them were resistant to ordinary antibiotics. Due to the low curative rate and the bad prognosis, the patients with advanced tumors need more active treatment for the primary affection(tumor)and antibiotics rationally using.

关 键 词：海洋石油职工 恶性肿瘤患者 医院感染分析 抗感染治疗 广谱抗菌素 条件致病菌 防治方法 临床特点 基本情况 临床疗效 培养结果 好发部位 G-杆菌 真菌感染 长期应用 肿瘤进展 并发 分析法 回顾性 大肠癌 呼吸道 消化道 病原体 

分 类 号：R181.3[医药卫生—流行病学]