超声波和Zn/蒙脱石-ZnCl_2使芳香醛片呐醇化  

Pinacolization of aromtic aldehydes using Zn/montmorillonite-ZnCl_2 and ultrasound

作　　者：刘清福[1] 翟建华[2] 庞国勋[3] 

机构地区：[1]邢台学院化学系,河北邢台054001 [2]河北科技大学国际交流与合作处,河北石家庄050018 [3]河北省人民医院药剂室,河北石家庄050071

出　　处：《河北科技大学学报》2005年第1期25-27,35,共4页Journal of Hebei University of Science and Technology

摘　　要：用超声波照射Ｚｎ/蒙脱石 ＺｎＣｌ_2和含50%(质量分数)ＴＨＦ的一些芳香醛水溶液2～3ｈ,芳香醛发生偶联反应,生成片呐醇,产率为23%～87%。2,4 二氯苯甲醛、β 苯基丙烯醛发生偶联反应时,片呐醇产率分别达到87.1%和74.8%;对甲基苯甲醛、糠醛发生偶联反应时,化学选择性较好;Ｚｎ/蒙脱石 ＺｎＣｌ_2重复使用3次,活性无显著降低。The coupling reaction aromtic aldehydes leading to pinacols were carried out by using Zn/montmorillonite-ZnCl_2 in 50% aqueous THF under ultrasound with 23%~87% yield.2,4-dichiorophenyl and β-benzaldehyde were coupled with 87.1% and 74.8% yields respectively.When occurs the reaction of pinacols p-methylbenzaldehyde and 2-furaldehyde , the chemistry selectivity is better; Zn/ montmorillonite-ZnCl_2 is repeatedly used for 3 times, with no active notable reduction. Contrasting experiment in progress goes deep into the study of this reaction . Its structure was characterized by IR, ~1H NMR and MS.The advantages of this method lie in moderate condition,high chemical selectivity,high yield and the reusability of the catalyst.

关 键 词：ZNCL2 芳香醛 偶联反应 产率 对甲基苯甲醛 醇化 二氯苯 化学选择性 水溶液 蒙脱石 

分 类 号：N941.5[自然科学总论—系统科学] O625[理学—有机化学]