连续性静脉静脉血液滤过治疗多器官功能障碍综合征的临床研究  

Influence of continuous venovenous hemofiltration on patients with multi pleorgan dysfunction syndrome.

作　　者：于长青[1] 林洪丽[1] 王可平[1] 杭宏东[1] 谢华[1] 王莉莉[1] 

机构地区：[1]大连医科大学附属第一医院肾内科,116011

出　　处：《中国实用内科杂志》2005年第4期342-344,共3页Chinese Journal of Practical Internal Medicine

摘　　要：目的研究连续性静脉静脉血液滤过治疗多脏器功能衰竭的疗效.方法1999-12～2003-12大连医科大学附属第一医院64例多器官功能障碍综合征(MODS)病人分为CVVH(静脉静脉血液滤过)治疗组34例和IHD(间歇性血液透析)治疗组30例,记录发生低血压、心律失常的次数,计算尿素清除指数(KT/V)值,治疗前后计算APACHE-Ⅱ评分并记录转归情况.结果CVVH治疗组血流动力学稳定性好于IHD治疗组;CVVH组KT/V值高于IHD组;CVVH组治疗后APACHE-Ⅱ评分好于IHD组,分别为(17.23±6.86)分,(20.91±5.77)分(P＜0.05).结论CVVH治疗在血流动力学稳定性,溶质清除率及预后方面优于IHD.Objective To study the influence of continous ven ovenuous hemofiltration on patients with multiple organ dysfunction syndrome.Methods 64 patients with MODS were divided into CVVH group(34) and IHD group(30)between 1999-12~2003-12.The serum BUN,Cr,iron,blood pressure,ar rhythmia were monitored during treatment and KT/V was also calculated after each therapy.APACHE-Ⅱ score was assessed before and after the treatment and the pr ognosis of each patient was recorded as well.Results CVVH group had more stable hemodynamics than IHD group; there was no significant difference in the removal of BUN and Cr in the two grou ps.The survival time of CVVH group was longer than IHD,and APACHE-Ⅱ score of C VVH group was lower than that in IHD group,17.23±6.86 verse 20.91±5.77 ( P<0.05),but the mortality of the two groups was the same.Conclusion Compared with IHD,CVVH has more advantage in hemodyn amics and solute clearance and prognosis.

关 键 词：CVVH IHD 血液滤过治疗 多器官功能障碍综合征 静脉血 治疗组 血流动力学 结论 大连医科大学 连续性 

分 类 号：R459.5[医药卫生—治疗学] R59[医药卫生—临床医学]