两种低张胶体液腹腔海水浸泡伤战地初步救治的实验效果  

Experimental study on field aid of celiac seawater immersion wound in the dogs

作　　者：刘献棠[1] 王志伟[1] 吴印爱[1] 蒋邦好[1] 金浩生[1] 谢尚奎[1] 黄建强[1] 

机构地区：[1]中国人民解放军广州军区第一五七中心医院普外科,广东广州510510

出　　处：《中国急救医学》2005年第4期262-263,共2页Chinese Journal of Critical Care Medicine

基　　金：广州军区后勤类重点课题(2001A14);广东省卫生厅2001年度立项课题(No.A2001517)

摘　　要：目的观察野战环境战地初步救治对腹腔海水浸泡伤实验犬生存的影响。方法杂种犬24只,随机均分为对照组(A组)、右旋糖酐40救治组(B组)及右旋糖酐70救治组(C组),观察每一组腹腔海水浸泡后的存活情况、血浆内毒素水平及组织病理学变化。结果①B、C两救治组长期存活率均为62 5%,显著高于对照组(P<0 05);②腹腔海水浸泡后12 h始B、C两救治组内毒素水平显著低于对照组;③对照组腹腔海水浸泡后24 h腹腔器官病理改变以化脓性炎症反应为主,而两救治组则以充血水肿性炎症反应为主。结论腹腔海水浸泡伤战地早期补入低张胶体液及完成初步清创能有效减轻机体腹腔感染,提高创伤动物生存率。Objective To observe effect of primary field aid on celiac seawater immersion wound in the dogs.Methods Twenty-four dogs were randomly divided into control group(group A),Dextran 40 aid group(group B)and Dextran 70 aid group(group C).Survival conditions were observed and plasma levels of endotoxin were measured after celiac seawater immersion in each group.Results ①Long-time survival rate was 62.5%(5/8) in group B and C and was longer significantly than that in group A(0/8)(P<0.05).②Plasma levels of endotoxin in group B and C became lower than those in group A(P<0.05)from 12 h after celiac seawater immersion.③24 h after celiac seawater immersion, the main pathological characteristics of celiac organs were purulent changes in group A, and edema and congestion in group B and C.Conclusion Early infusion of hypotonic liquid containing colloid and celiac debridement can reduce degrees of celiac infection and improve survival rate in field aid of celiac seawater immersion wound. [

关 键 词：腹部外伤 海水浸泡 战地救治 

分 类 号：R826[医药卫生—临床医学]