聚氨酯硬段改性材料心室辅助装置血液相容性及毒理学研究  

The Study on Blood Compatibility and Toxicology of Polyurethane's Hard Segments Modified Ventricular Assistant Device

作　　者：刘金成[1] 易定华[1] 徐学增[1] 贾林才[1] 赵雨花[1] 胡巧侠[1] 

机构地区：[1]第四军医大学西京医院心血管外科,西安710032

出　　处：《北京生物医学工程》2005年第2期81-83,96,共4页Beijing Biomedical Engineering

基　　金：陕西省西安市科学技术创新基金 (ZS2 0 0 2 15 )资助

摘　　要：通过溶血试验、动态凝血时间试验、血小板黏附试验及全身急毒试验 ,评价聚氨酯硬段改性材料作为人工心室辅助装置材料的血液相容性和全身毒性 ,结果显示硬段改性聚氨酯材料血液相容性优于未改性聚氨酯材料 ,无明显全身毒性反应。In this research, polyurethane's hard segments modified ventricular assistant device of blood compatibility and toxicology characteristics were evaluated using hemolysis test,the dynamic cruor time test,the adhesion of blood platelet test, and systemic injection test. The results show modified polyurethane's is better in blood compatibility than that without modified polyurethane's, Modified polyurethane's does not have significant toxicology.

关 键 词：聚氨酯 心室辅助装置 血液相容性 毒理学 改性材料 

分 类 号：R318.11[医药卫生—生物医学工程]