叶酸中三氯丙酮和有机溶剂残留量的毛细管GC测定  

Determination of Trichloroacetone and Residual Organic Solvents in Folic Acid by Capillary GC

作　　者：田宝娟[1] 李志伟[2] 王孟歌[1] 阎宏远[1] 

机构地区：[1]保定师范专科学校,河北保定071051 [2]河北大学药学院,河北保定071002

出　　处：《中国医药工业杂志》2005年第4期237-238,共2页Chinese Journal of Pharmaceuticals

摘　　要：A capillary GC method was established for determination of1,1,3-trichloroacetone and residual organic solvents methanol, toluene in folic acid. The detection limits were 80, 1.5 and 2ng, respectively. The average recover- ies were 98.0%(RSD 3.8%), 97.5%(RSD 2.9%) and 102.0%(RSD 4.5%), respectively.A capillary GC method was established for determination of1,1,3-trichloroacetone and residual organic solvents methanol, toluene in folic acid. The detection limits were 80, 1.5 and 2ng, respectively. The average recover- ies were 98.0%(RSD 3.8%), 97.5%(RSD 2.9%) and 102.0%(RSD 4.5%), respectively.

关 键 词：有机溶剂残留量 毛细管 氯丙酮 测定 水溶性B族维生素 叶酸缺乏症 溶血性贫血 acid 细胞生长 合成过程 用药安全 产品质量 GC法 物质 甲醇 原药 甲苯 

分 类 号：TQ460.72[医药卫生—药物分析学] O657.8[化学工程—制药化工]